Immediate action

Wash. Encourage bleeding. Notify A&E or Occupational Health within 1 hour. HIV PEP best <1–2h, up to 72h.

🇬🇧 United Kingdom 🇬🇧 United Kingdom · UKHSA Green Book Ch 12 · BASHH/EAGA · RIDDOR 2013

Occupational post-exposure prophylaxis (PEP)

Decision support for a significant occupational exposure to blood or body fluids — sharps injury, mucocutaneous splash or bite — in healthcare and other at-risk workers. HIV PEPSE follows BASHH/EAGA; HBV and surveillance follow the UKHSA Green Book Chapter 12 occupational pathway, alongside your local Trust Occupational Health policy.

Exposure risk-assessment wizard

Local computation, no worker or source data stored. Suggests options under the clinician's judgement.

Emergency contacts

Local Trust Occupational Health (24/7)

First point of contact for in-hours significant exposures — risk assessment, source consent, HBIG / PEP supply.

A&E — out of hours

Out-of-hours route for the time-critical first dose of HIV PEP and HBIG.

UKHSA Health Protection Team

Notifiable-disease advice and outbreak / source liaison (Health Protection (Notification) Regulations 2010).

BASHH/EAGA HIV PEP guidance

https://www.bashh.org/guidelines

Related tools

Under the physician's clinical judgement

  • Time-critical decisions — clinical judgement takes precedence over the wizard; do not delay the first PEP dose to complete the tool.
  • Testing the worker requires their informed consent; source-person testing requires the source's own consent (GMC).
  • Confidentiality — the source's identity and results are not shared with the exposed worker.
  • Completion of the significant occupational exposure form is mandatory for percutaneous / mucocutaneous exposures.

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