Immediate action
Wash exposed area with soap + water (eyes: irrigate 15+ minutes) · Encourage bleeding from puncture site · Notify Employee Health Service / OH immediately · HIV PEP best <2 hours, effective up to 72h (CDC 2024) · Complete OSHA Sharps Injury Log + Exposure Incident Report
Occupational post-exposure prophylaxis (PEP)
Decision support for a significant occupational exposure to blood or other potentially infectious body fluids — sharps injury, mucocutaneous splash or bite — in healthcare and other at-risk workers. HIV PEP follows CDC/USPHS occupational guidance; HBV and HCV management follow CDC; recordkeeping follows the OSHA Bloodborne Pathogens Standard (29 CFR 1910.1030) and your facility's Exposure Control Plan.
Exposure risk-assessment wizard
Local computation, no worker or source data stored. Suggests options under the clinician's judgement.
Emergency contacts
CDC HIV PEPline — 24/7 (healthcare providers)
1-888-448-4911National Clinicians' Post-Exposure Prophylaxis Hotline — real-time advice on occupational HIV/HBV/HCV PEP.
Local Employee Health Service
First point of contact for in-hours exposures — risk assessment, source consent, HBIG / PEP supply. [Add your facility's number]
Hospital Emergency Department — out of hours
Out-of-hours route for the time-critical first dose of HIV PEP and HBIG when Occupational Health is unavailable.
CDC occupational PEP guidance
https://www.cdc.gov/niosh/topics/bbp/Related tools
Under the physician's clinical judgement
- Time-critical decisions — clinical judgement takes precedence over the wizard; do not delay the first HIV PEP dose to complete the tool.
- Source-person testing requires consent (HIPAA + applicable state laws; some states permit testing without consent for HCP occupational exposure).
- Testing the exposed worker requires their informed consent.
- Confidentiality — the source's identity and results are not shared with the exposed worker.
- The Exposure Incident Report is kept separate from the worker's medical record.
- An entry in the OSHA Sharps Injury Log is mandatory for contaminated sharps injuries (29 CFR 1910.1030(h)(5)).
- Note the HIPAA dual nature of OH records — occupational health records may be treated as employment records rather than protected health information in some contexts.