OSHA Recordkeeping Standard
link29 CFR 1904
Defines work-relatedness (29 CFR 1904.5) and recording criteria (1904.7) for the OSHA 300 log
There is no unified federal occupational-disease list in the US — unlike the UK's IIDB Prescribed Diseases (PD A1–D12) or Spain's closed-list RD 1299/2006. This catalogue is a synthesis of 70 occupational diseases built from BLS SOII + OSHA 29 CFR 1904 recordkeeping + NIOSH surveillance, bound to ICD-10-CM codes and 50-state workers'-compensation presumption variation.
There is no U.S. federal equivalent to Spain's RD 1299/2006 closed-list catalog. Work-relatedness is determined case-by-case under state workers' compensation laws (50 systems) and OSHA recordkeeping.
This fragmentation is structural, not an anomaly: work-relatedness is decided case-by-case across 50 state workers'-comp systems, layered on OSHA recordkeeping and federal surveillance.
The federal surveillance + recordkeeping scaffolding that replaces a single statutory list.
29 CFR 1904
Defines work-relatedness (29 CFR 1904.5) and recording criteria (1904.7) for the OSHA 300 log
29 CFR 1910 Subpart Z
Substance-specific PELs and surveillance triggers
29 CFR 1910.1030
BBP HBV/HCV/HIV exposures
Bureau of Labor Statistics SOII
Annual surveillance; 7 illness categories on Form 300
NIOSH WoRLD
Surveillance of asbestos, coal, silica, beryllium, asthma, HP
Y96 (Work environment), Z57.x (Occupational exposure)
Diagnostic coding for occupational nature
James Zadroga 9/11 Health and Compensation Act
Federally-funded health monitoring for 9/11 responders/survivors
EEOICPA + DOE FWP
DOE nuclear weapons / energy workers
30 USC §901 et seq.
Coal miner pneumoconiosis benefits administered by OWCP
OSHA Form 300 — illness columns
29 CFR 1904 records work-related cases but does NOT enumerate diseases.
Default notification pathways
Arsenicism (chronic): peripheral neuropathy, dyskeratosis, hyperpigmentation, anemia; lung/skin/bladder cancer in Group 6
ICD-10-CM T57.0X1A · T57.0X4A · Z57.4 · Z77.018
Key exposures: Smelting of copper, lead, zinc with arsenic-containing ores; Semiconductor (GaAs) manufacturing; Pesticide / herbicide / wood preservative manufacture (CCA, MSMA); Glass industry decolorization; Coal-fired power plant cleanup; Mining of arsenic-bearing ores
Biological markers: Urinary arsenic (sum of inorganic + monomethyl + dimethyl species) — BEI 35 ug/L (referenced; ACGIH copyright); Hair/nail arsenic — environmental indicator only, not biological monitoring
NIOSH: ABLES (focused on lead but ABLES network used for some As cluster investigations); NHANES population reference
Notification: OSHA 300 M(3); state WC; CDC NIOSH consultation if cluster
Chronic Beryllium Disease (CBD), beryllium sensitization (BeS), acute beryllium pneumonitis
ICD-10-CM J63.2 · Z57.5 · T56.7X1A
Key exposures: Beryllium machining (aerospace, electronics); Nuclear weapons component manufacture (DOE sites); Dental laboratory work with Be alloys; Ceramics manufacture; Metal recycling
Biological markers: Beryllium Lymphocyte Proliferation Test (BeLPT) — definitive screen for sensitization
NIOSH: DOE FWP includes BeLPT; CBD listed in NIOSH WoRLD pneumoconiosis category
Notification: OSHA 300 M(2); DOE FWP if DOE-related; state WC; EEOICPA claim if DOE/AWE site exposure
Cadmium nephropathy (tubular proteinuria), pulmonary disease (acute pneumonitis, chronic), itai-itai-like osteomalacia; lung/prostate cancer in Group 6
ICD-10-CM N14.3 · J68.0 · T56.3X1A
Key exposures: Battery manufacture (NiCd); Electroplating; Pigment manufacture (CdS, CdSe); Brazing/soldering with Cd-containing alloys; PVC stabilizer manufacture; Solar cell (CdTe) manufacture; Smelting/refining of zinc, lead, copper
Biological markers: Cadmium in blood (CdB) — recent exposure; Cadmium in urine (CdU) — body burden, normalize to creatinine; Beta-2-microglobulin in urine — early renal effect; Retinol-binding protein urine
NIOSH: Cadmium monitoring required by OSHA 1910.1027 for exposed workers
Notification: OSHA 300; state WC
Cr(VI) ulcerations (nasal septum perforation), allergic contact dermatitis, asthma; sinonasal/lung cancer in Group 6
ICD-10-CM J68.2 · J30.81 · L23.0 · T56.2X1A
Key exposures: Electroplating (hard chrome); Stainless steel welding (especially MIG/MMA); Leather tanning; Chromate pigment manufacture; Wood preservation (CCA); Cement and concrete (trace Cr(VI))
Biological markers: Urinary chromium end-of-shift end-of-workweek
NIOSH: OSHA medical surveillance if exposure >=action level (2.5 ug/m3)
Notification: OSHA 300; state WC
Plumbism: peripheral neuropathy, encephalopathy, anemia (microcytic/hypochromic), nephropathy, hypertension, reproductive effects, lead colic
ICD-10-CM T56.0X1A · T56.0X4A · G62.2
Key exposures: Battery manufacture and recycling; Lead smelting/refining; Construction trades — abrasive blasting, demolition, welding of painted steel; Firing ranges (commercial and indoor); Radiator repair (legacy); Pottery and stained glass (legacy); Bridge / steel structure painting / abatement; Ammunition manufacture; Lead-based paint abatement
Biological markers: Blood lead level (BLL) — primary surveillance test; Zinc protoporphyrin (ZPP); ALA-D erythrocyte (research); Urinary lead — limited utility
Medical removal: OSHA general industry: BLL >=60 ug/dL (or 3 consecutive >=50). Construction: >=50 (or 3 >=40). NIOSH/CDC ABLES recommends action at BLL >=5 ug/dL. CDC CDC adult reference BLL is <3.5 ug/dL (2021 update from 5).
NIOSH: ABLES (Adult Blood Lead Epidemiology and Surveillance) — CDC funded in ~30 states
Notification: OSHA 300 M(3); state ABLES program; state WC
Mercurialism: erethism, tremor, gingivitis (elemental); methylmercury — neurologic (cerebellar/visual); inorganic — nephropathy; acrodynia (children)
ICD-10-CM T56.1X1A · G62.2 · N14.3
Key exposures: Dental amalgam preparation (legacy and current low-level); Thermometer/barometer manufacture (legacy); Chlor-alkali plants (largely closed by 2013); Gold mining (artisanal — DOE/state cleanup workers); Fluorescent lamp recycling; Mining of cinnabar (legacy); Hg-containing waste disposal
Biological markers: Urinary mercury (Hg-U) — body burden inorganic + elemental; Blood mercury (Hg-B) — methylmercury preferred
NIOSH: Some state biomonitoring programs
Notification: OSHA 300; state WC; CDC NCHS NHANES population reference
Manganism: parkinsonian syndrome (resting tremor less prominent than idiopathic PD; gait disturbance and cock-walk; psychiatric prodrome)
ICD-10-CM T57.2X1A · G21.8
Key exposures: Welding (especially of mild and stainless steel — fume contains Mn); Dry battery manufacture; Ferromanganese alloy production; Mn ore mining and milling; Welder's grinding
Biological markers: Blood Mn (limited specificity); MRI brain T1-weighted globus pallidus hyperintensity (biological effect, not biomarker proper)
NIOSH: Welding fume surveillance under multiple substance-specific NIOSH bulletins
Notification: OSHA 300; state WC
Nickel allergic contact dermatitis; respiratory sensitization. (Nickel refining / inhaled compound carcinogens in Group 6)
ICD-10-CM L23.0 · J45.998 · T56.891A
Key exposures: Nickel plating; Stainless steel manufacture and welding; Coin handling (cashiers — non-occupational mostly); Jewelry making; Battery manufacture (NiCd, NiMH)
Biological markers: Patch testing for sensitization (clinical, not surveillance)
Notification: OSHA 300; state WC
Aplastic anemia, myelodysplastic syndrome, pancytopenia. (Acute leukemia in Group 6.)
ICD-10-CM D61.2 · T52.1X1A · Z57.5
Key exposures: Petroleum refining (BTX recovery); Coke oven operations; Rubber manufacturing; Solvent use in industry (largely phased out as bulk solvent); Gasoline distribution and retail (low-level); Chemical manufacture using benzene intermediates
Biological markers: Urinary trans,trans-muconic acid (ttMA); Urinary S-phenylmercapturic acid (S-PMA) — more specific
NIOSH: OSHA 1910.1028 medical surveillance required >=action level
Notification: OSHA 300; state WC
Toluene encephalopathy (chronic — cognitive decline, cerebellar dysfunction), acute CNS depression, ototoxicity (synergistic with noise)
ICD-10-CM G92 · T52.2X1A · H93.099
Key exposures: Paint and lacquer manufacture and application; Adhesive manufacture (especially in shoe and leather); Printing; Solvent abuse occupational settings (rare but documented); Toluene-based degreasing
Biological markers: Urinary o-cresol — preferred specific; Urinary hippuric acid — non-specific (also from food)
Ototoxicity: NIOSH ototoxicity flag — toluene exposure synergizes with noise; consider co-surveillance audiometry
Notification: OSHA 300; state WC
Styrene encephalopathy, ototoxicity, reproductive effects. (Probable carcinogen IARC 2B — group 6 if confirmed.)
ICD-10-CM G92 · T52.4X1A
Key exposures: Glass fiber-reinforced plastic (GFRP) lay-up (boat, bathtub, automotive parts); Polystyrene manufacturing; Synthetic rubber (SBR) production; Resin and composite work
Biological markers: Urinary mandelic acid + phenylglyoxylic acid (end-of-shift)
Notification: OSHA 300; state WC
Distal symmetric sensorimotor axonal polyneuropathy (legs first, ascending). Visual impairment in severe cases.
ICD-10-CM G62.2 · T52.0X1A
Key exposures: Shoe and leather adhesive manufacture; Furniture finishing; Printing solvent; Vegetable oil extraction (refineries); Auto repair shop solvent use
Biological markers: Urinary 2,5-hexanedione (end-of-shift, end-of-workweek)
Notification: OSHA 300; state WC
Acute CNS depression, COHb elevation (metabolism to CO), hepatic effects. Banned from consumer paint stripper 2019. (IARC 2A; cancer in Group 6.)
ICD-10-CM T53.4X1A · G92
Key exposures: Paint stripping (commercial only as of EPA 2019 rule); Pharmaceutical manufacture; Adhesive and aerosol manufacture; Plastics processing
Biological markers: COHb at end-of-shift; Urinary DCM
Notification: OSHA 300; state WC; EPA reporting for commercial paint strip
Liver injury, renal effects, dermatitis. IARC Group 1 — kidney cancer in Group 6.
ICD-10-CM K71.3 · T53.2X1A
Key exposures: Metal degreasing (largely phased out post-2000 in U.S.); Solvent in adhesives; Dry cleaning (PCE/perc primarily but TCE secondary); Aerospace cleaning operations
Biological markers: Urinary trichloroacetic acid (TCA); Urinary trichloroethanol
Notification: OSHA 300; state WC; EPA TSCA risk evaluation 2020 -- restrictions advancing
Irritant contact dermatitis, asthma, allergic contact dermatitis. IARC Group 1 — nasopharyngeal cancer + myeloid leukemia in Group 6.
ICD-10-CM L23.5 · J68.3 · T59.2X1A
Key exposures: Anatomy / pathology laboratories (embalming, tissue fixation); Mortuary work; Particle board / plywood / OSB manufacture; Textile finishing (permanent press); Foundry core-making (phenol-formaldehyde resin)
Biological markers: No reliable biomarker; environmental measurement primary
Notification: OSHA 300; state WC
Occupational asthma, allergic contact dermatitis, irritant contact dermatitis, conjunctivitis
ICD-10-CM J45.998 · L23.5 · H10.45
Key exposures: High-level disinfection of endoscopes / instruments in healthcare; Cold sterilization solutions; X-ray film developing (legacy); Embalming
Biological markers: None standardized
Notification: OSHA 300; state WC
Occupational asthma (LMW sensitizer), hypersensitivity pneumonitis, allergic rhinitis, contact dermatitis
ICD-10-CM J45.998 · J67.8 · J30.81
Key exposures: Polyurethane foam manufacture (rigid and flexible); Spray-applied polyurethane insulation (SPF); Automotive painting (urethane clear coats); Adhesive manufacture; Coatings application; Cast-elastomer manufacture
Biological markers: Urinary TDA / MDA (diamine metabolites); Specific IgE / IgG antibody (limited clinical)
NIOSH: Spray polyurethane foam industry HHEs
Notification: OSHA 300; state WC
Acute CO poisoning (hypoxic encephalopathy), chronic neuropsychiatric sequelae
ICD-10-CM T58.01XA · T58.91XA · G93.41
Key exposures: Indoor use of fuel-powered equipment (forklifts, generators, pressure washers); Firefighting (smoke inhalation); Auto repair (running engines indoors); Charcoal production; Iron and steel foundry / blast furnace; Mining
Biological markers: Carboxyhemoglobin (COHb) — venous or arterial; SpCO via co-oximetry; Reference: nonsmoker <2%, smoker <10%
Notification: OSHA 300; state WC; OSHA 1904.39 reporting if hospitalization
Acute H2S poisoning (knockdown / respiratory paralysis), chronic neurocognitive effects, ocular irritation (keratoconjunctivitis 'gas eye')
ICD-10-CM T59.6X1A · G92
Key exposures: Oil and gas extraction (sour crude); Confined space entry — sewers, manholes, tanks; Pulp and paper kraft mill; Hog/swine manure pits (lethal incidents documented); Hot springs work; Rendering plants; Tannery work
Biological markers: Urinary thiosulfate (acute, post-exposure)
Notification: OSHA 300; OSHA 1904.39 (fatalities common); state WC
Acute cholinergic syndrome (SLUDGE/Killer B's), intermediate syndrome, OPIDN (organophosphate-induced delayed polyneuropathy)
ICD-10-CM T60.0X1A · T60.0X4A · G62.2
Key exposures: Agricultural pesticide application (chlorpyrifos restricted in food crops 2021 EPA, partially reinstated 2024); Vector control (mosquito spraying — malathion); Greenhouse work; Veterinary use (livestock dipping — legacy); Termite control (organophosphates restricted)
Biological markers: Erythrocyte acetylcholinesterase (AChE) — baseline pre-season + during season; Plasma butyrylcholinesterase (BuChE) — less specific; Urinary dialkyl phosphates
NIOSH: California SENSOR-Pesticides program; CDC NIOSH pesticide registry
Notification: OSHA 300; state pesticide regulatory authority; EPA WPS; state WC
Noise-induced hearing loss (sensorineural, bilateral, symmetric, 4 kHz notch initially), tinnitus
ICD-10-CM H83.3 · H93.13 · Z57.0
Key exposures: Construction (heavy equipment, jackhammers); Manufacturing (stamping, grinding); Mining; Agriculture (tractor cabs improved but still risk); Aviation and aerospace (ground crew, military); Music venues, entertainment; Public safety sirens (EMS/police/fire)
Biological markers: Baseline audiogram + annual audiogram; STS (Standard Threshold Shift) = >=10 dB average 2/3/4 kHz
NIOSH: BLS Annual data; NIOSH surveillance NHIS sub-questions
Notification: OSHA 300 M(4) if STS + at-risk + age-correction applied; state WC
Hand-arm vibration syndrome (HAVS): vascular (Raynaud's phenomenon vibration-induced 'white finger'), neurologic (paresthesias, dexterity loss), musculoskeletal
ICD-10-CM T75.21XA · I73.00
Key exposures: Chainsaw operators (logging, tree care); Grinder / sander / chipper / impact wrench operators; Pneumatic tool use (construction, manufacturing); Jackhammer operators; Dental hygienists (sustained instrument use)
Biological markers: Cold provocation test; Stockholm Workshop Scale classification (vascular + sensorineural)
NIOSH: NIOSH HAV criteria document 1989; no formal national surveillance
Notification: OSHA 300 M(5); state WC
Acute radiation syndrome, radiation dermatitis, cataract, hypothyroidism, sterility. Cancer in Group 6.
ICD-10-CM T66.XXXA · L58.9 · H26.8
Key exposures: Healthcare — interventional radiology, nuclear medicine, radiation oncology; Nuclear power industry; Industrial radiography (NDT); Uranium mining and milling (historical and current); DOE nuclear weapons complex workers; Research labs with radioisotopes
Biological markers: Personal dosimeter (TLD or OSL); Cytogenetic dose reconstruction (lymphocyte chromosomal aberrations) — retrospective
NIOSH: NIOSH-DOE Former Worker Medical Surveillance Program (FWP); SEER linkage for some occupations
Notification: NRC reporting; DOE FWP if DOE-related; OWCP EEOICPA claim for DOE/AWE; state WC
Heat exhaustion, heat stroke, heat cramps, heat syncope, rhabdomyolysis, AKI
ICD-10-CM T67.0XXA · T67.3XXA · T67.5XXA · M62.82 · N17.9
Key exposures: Outdoor agriculture (especially harvest); Construction (especially roofing, asphalt); Warehouse / parcel delivery (high-profile UPS, Amazon issues); Firefighters (structural and wildland); Foundries, glass, kitchens, laundries; Military training
Biological markers: Core temp (if measured) >=104°F (40°C) = heat stroke; AKI markers; Rhabdo: CK >5x ULN; Acclimatization status
NIOSH: NIOSH Criteria for a Recommended Standard: Occupational Exposure to Heat 2016 update
Notification: OSHA 300 M(5); OSHA 1904.39 if hospitalization or fatality; state WC
State overlays: CA 8 CCR 3395 (outdoor and indoor); OR OAR 437-002-0156; WA WAC 296-307 / 296-62; CO HB22-1248; MN 5205.0110 (indoor)
Acute respiratory irritation, asthma exacerbation, reduced lung function, cardiovascular events; chronic exposure associations under study
ICD-10-CM J68.3 · J45.901 · J70.8 · R06.02
Key exposures: Wildland firefighters (highest exposure); Outdoor agricultural workers during fire season; Construction + landscaping outdoor workers; Utility + forestry workers; Outdoor workers in fire-prone regions (West Coast, Mountain West, increasingly Canada-smoke-affected Northeast/Midwest)
Biological markers: Spirometry (FEV1/FVC pre/post season); Symptom + AQI exposure diary; Pulse oximetry during exposure
NIOSH: NIOSH wildland firefighter health studies; CDC/ATSDR PM2.5 health tracking
Notification: OSHA 300 M(2) if work-related respiratory; state WC; state air quality program
Decompression sickness (DCS Type I limb pain, Type II neurologic), arterial gas embolism, dysbaric osteonecrosis, barotrauma
ICD-10-CM T70.3XXA · T70.29XA · M87.81
Key exposures: Commercial diving (oil and gas, salvage); Caisson workers (tunneling); Hyperbaric chamber operators (medical hyperbaric); Aviation (high altitude, U-2 pilots); Astronauts
Biological markers: DCI risk indices, dive computer records, Doppler bubble detection
Notification: OSHA 300; state WC; USCG / OSHA Diving Operations reporting
Acute and chronic hepatitis B; chronic liver disease; HCC in Group 6
ICD-10-CM B16.9 · B18.1 · Z20.5 · Z57.5
Key exposures: Healthcare workers — needlesticks, splashes; First responders / EMS; Laboratory workers handling blood/tissue; Mortuary workers; Correctional health staff; Tattoo artists / body piercers; Dialysis patients and staff
Biological markers: HBsAg, anti-HBs (immunity post-vaccine >=10 mIU/mL), anti-HBc (past infection), HBeAg, HBV DNA (replication)
Post-exposure: Per CDC USPHS PEP guidelines: HBV PEP within 24h; HBIG if non-immune source HBsAg+
Notification: OSHA 300; CDC NNDSS (acute HBV is nationally notifiable); state WC; OSHA Sharps Injury Log mandatory under 1910.1030
Acute and chronic hepatitis C; cirrhosis; HCC in Group 6
ICD-10-CM B17.10 · B18.2 · Z20.5
Key exposures: Same as HBV — primary needlestick risk in healthcare; also dialysis, tattoo, BBF exposures
Biological markers: Anti-HCV (seroconversion 1-3 months), HCV RNA (acute or active infection)
Post-exposure: Per CDC: no PEP; serial monitoring anti-HCV + RNA at 0, 3, 6 weeks (or HCV RNA at 3-6 weeks), then anti-HCV at 4-6 months. DAA treatment if seroconversion (95%+ cure).
Notification: OSHA 300; CDC NNDSS (acute HCV nationally notifiable since 2016); state WC
Acute retroviral syndrome (seroconversion illness), AIDS
ICD-10-CM B20 · Z21 · Z20.6
Key exposures: Healthcare needlestick / mucocutaneous BBF exposure (low risk per exposure ~0.3% percutaneous, ~0.1% mucosal); Research lab with HIV concentrates
Biological markers: 4th gen Ag/Ab combo at 0, 6, 12 weeks post-exposure; HIV RNA if symptomatic seroconversion
Post-exposure: USPHS PEP within 72h (preferably <2h): 3-drug regimen (TDF/FTC + raltegravir or dolutegravir) x 28 days
Notification: OSHA 300; CDC NNDSS (HIV nationally notifiable); state WC
Latent TB infection (LTBI), active pulmonary TB, extrapulmonary TB
ICD-10-CM A15.0 · A15.9 · Z20.1 · Z57.5
Key exposures: Healthcare personnel (especially correctional, homeless services, ID); Correctional officers; Homeless services personnel; Lab workers handling MTB cultures; First responders responding to congregate settings
Biological markers: IGRA (T-SPOT.TB or QuantiFERON) preferred over TST in BCG-vaccinated; Chest X-ray if positive
Screening: CDC MMWR 2019 (Sosa et al): baseline IGRA at hire for HCP; annual NOT recommended unless ongoing exposure
Notification: OSHA 300; CDC NNDSS (active TB nationally notifiable); state WC; state public health TB control
Conjunctivitis, mild respiratory illness, severe ARDS in rare cases
ICD-10-CM J09.X9 · Z20.828
Key exposures: Poultry workers (broiler, layer, breeder operations); Dairy workers (US 2024-2026 dairy H5N1 outbreak — first mammalian dairy transmission); Wildlife / wild bird response personnel; Veterinarians and lab personnel
Biological markers: RT-PCR from conjunctival or respiratory swab; Serology (HI or microneutralization)
Post-exposure: Oseltamivir prophylaxis per CDC; PPE per CDC HAI guidance (eye protection critical)
Notification: OSHA 300; CDC HAN; state public health; USDA APHIS for animal cases
Brucellosis (undulant fever): fever, sweats, arthralgia, hepatosplenomegaly, endocarditis (severe)
ICD-10-CM A23.9 · Z20.821
Key exposures: Slaughterhouse workers (cattle, swine, goats); Veterinarians, lab workers; Dairy workers (raw milk); Hunters (feral swine — wild Suis brucellosis)
Biological markers: Serology (Brucella agglutination), blood culture, PCR
Notification: OSHA 300; CDC NNDSS; state public health; USDA APHIS animal cases
Acute Q fever (pneumonia, hepatitis), chronic Q fever (endocarditis)
ICD-10-CM A78 · Z20.828
Key exposures: Livestock workers (especially small ruminants — sheep/goats parturition); Slaughterhouse personnel; Lab workers (highest risk — Coxiella BSL-3); Veterinarians; Wool/hide handlers
Biological markers: Serology IgM and IgG to phase I and phase II antigens; PCR from blood
Notification: OSHA 300; CDC NNDSS; state public health; military notification (Iraq/Afghanistan veterans)
Early localized (erythema migrans), early disseminated (carditis, neurologic), late (arthritis, post-treatment Lyme)
ICD-10-CM A69.20 · A69.21 · A69.22 · A69.23
Key exposures: Outdoor workers in endemic Northeast/Mid-Atlantic/upper Midwest: forestry, surveying, utility line work, park rangers, landscapers, agricultural
Biological markers: 2-tier serology (ELISA + Western Blot) per CDC; PCR limited
Notification: OSHA 300; state public health (most states reportable); state WC
Acute progressive encephalitis (~100% fatal once symptomatic)
ICD-10-CM A82.9 · Z20.3
Key exposures: Veterinarians and staff; Animal control officers; Wildlife biologists, spelunkers; Lab workers handling rabies virus
Biological markers: Anti-rabies neutralizing antibody titer (>0.5 IU/mL = adequate)
Post-exposure: PEP per ACIP 2022: 2 doses if previously vaccinated; 4 doses + HRIG if not
Notification: OSHA 300; state public health; CDC NNDSS for human cases
Acute COVID-19, post-acute sequelae of SARS-CoV-2 (PASC / Long COVID)
ICD-10-CM U07.1 · U09.9 · Z20.822
Key exposures: Healthcare personnel (highest risk in early pandemic); Long-term care personnel; Correctional officers; Meatpacking workers (cluster outbreaks 2020); First responders; Public transit personnel; Retail and grocery workers (essential designation)
Biological markers: RT-PCR, antigen test, antibody (post-infection vs post-vaccine differentiation: N protein vs S protein)
Notification: OSHA 300 (per OSHA enforcement memos); CDC NNDSS; state public health; OSHA 1904.39 if hospitalization/fatality work-related
Mpox: vesiculopustular rash, lymphadenopathy, fever
ICD-10-CM B04 · Z20.828
Key exposures: Healthcare personnel caring for mpox patients; Laboratory personnel handling MPXV; Veterinarians (mpox in mammalian hosts); Public health investigators
Biological markers: MPXV PCR from lesion swab; orthopoxvirus IgG
Post-exposure: JYNNEOS PEP within 4 days (ideally) to 14 days post-exposure
Notification: OSHA 300; CDC NNDSS (mpox nationally notifiable 2022); state public health
Silicosis (simple chronic, accelerated, acute, PMF), silicotuberculosis, COPD, autoimmune disease (silicosis-scleroderma)
ICD-10-CM J62.8 · J65 · J68.1 · M34.83
Key exposures: Stone fabrication (engineered stone / quartz countertops — EPIDEMIC of accelerated silicosis 2018-2026 in CA, FL, TX, NY); Sandblasting (abrasive blasting — banned for many uses); Construction (concrete/masonry cutting, drilling); Mining and quarrying; Foundry work; Hydraulic fracturing (frac sand operations)
Biological markers: Chest X-ray with ILO classification by NIOSH B-reader (small rounded opacities upper zones); HRCT in symptomatic cases; PFT (restrictive +/- obstructive)
NIOSH: NIOSH WoRLD silicosis surveillance; California Silicosis Surveillance Program (post-engineered stone epidemic)
Notification: OSHA 300 M(2); state silicosis registry (MI, NJ, CA reportable); state WC; NIOSH HHE if outbreak
Asbestosis, pleural plaques, diffuse pleural thickening, benign asbestos pleural effusion. Mesothelioma + lung cancer in Group 6.
ICD-10-CM J61 · J92.0 · J94.8
Key exposures: Insulation work (legacy); Shipbuilding (especially WWII era); Construction trades — demolition/renovation of pre-1980 buildings; Asbestos abatement; Auto brake repair (legacy); 9/11 WTC responders/survivors
Biological markers: Chest X-ray ILO classification (B-reader): irregular opacities lower zones; pleural plaques; HRCT; PFT (restrictive); Fiber burden analysis (lung biopsy — historical)
NIOSH: NIOSH WoRLD asbestosis tracking; CDC ATSDR asbestos community surveillance
Notification: OSHA 300; state WC; EPA AHERA (asbestos in schools); EPA TSCA final rule 89 FR 21970 (March 28, 2024; effective May 28, 2024) chrysotile ban; WTC Health Program if 9/11 eligible
Coal worker's pneumoconiosis (CWP simple and complicated/PMF), 'Black Lung'; dust-related diffuse fibrosis; COPD
ICD-10-CM J60 · J64
Key exposures: Underground coal mining; Surface coal mining (less risk); Coal handling
Biological markers: Chest X-ray ILO classification by NIOSH B-reader (small rounded opacities upper zones — different from silica which has more nodular); Spirometry
NIOSH: NIOSH Coal Workers' Health Surveillance Program (CWHSP) — free X-ray and spirometry; resurgence of CWP in central Appalachia documented 2010s-2020s
Notification: MSHA reporting; OWCP Black Lung Benefits Act claim (federal); state WC
Hard metal lung disease (giant cell interstitial pneumonia, GIP); occupational asthma to cobalt
ICD-10-CM J84.114 · J45.998
Key exposures: Tungsten carbide tool manufacture (saw blades, drill bits); Diamond polishing with cobalt-tungsten binders; Grinding of hard metal tools
Biological markers: BAL with multinucleated giant cells (cannonball cells); HRCT with peripheral GGO and reticulation
Notification: OSHA 300; state WC
Sensitizer-induced occupational asthma; work-related allergic rhinoconjunctivitis
ICD-10-CM J45.998 · J30.81
Key exposures: Bakers (wheat flour — Baker's asthma); Lab animal workers (rat, mouse urinary proteins); Healthcare (latex prior to powder-free transition); Veterinarians; Pharmaceutical (psyllium); Detergent enzyme manufacture
Biological markers: Spirometry (pre/post shift, serial peak flow 4x/day with work diary); Methacholine challenge; Specific IgE; Specific inhalation challenge (specialized centers)
NIOSH: NIOSH WoRLD Occupational Asthma Surveillance
Notification: OSHA 300; state surveillance (CA SENSOR-Asthma, MI, MA, NJ); state WC
Sensitizer-induced occupational asthma — LMW; reactive airways dysfunction syndrome (RADS) from high-level exposure
ICD-10-CM J45.998 · J68.3
Key exposures: Spray polyurethane foam (isocyanates); Hairdressing (persulfate bleaches); Auto refinish painting; Solder fume (colophony/rosin); Pharmaceutical manufacture
Biological markers: Specific inhalation challenge (gold standard but rare in US); Serial peak flow + spirometry; Specific IgE inconsistently available for LMW
Notification: OSHA 300; state SENSOR-Asthma; state WC
Work-exacerbated asthma (WEA) — pre-existing asthma exacerbated by irritants or allergens at work
ICD-10-CM J45.901
Key exposures: Cleaning products (chlorine bleach, ammonia, QUATS); Construction dust; Diesel exhaust; Cold air
Biological markers: Improvement away from work documented; peak flow correlation
Notification: OSHA 300; state SENSOR-Asthma; state WC
HP: acute (fevers, dyspnea, restrictive), chronic (fibrotic, indistinguishable from IPF if advanced)
ICD-10-CM J67.0 · J67.1 · J67.8 · J67.9
Key exposures: Farmers (moldy hay — Farmer's lung); Bird breeders/owners (Bird fancier's lung); Hot tub maintenance (Hot tub lung — atypical mycobacteria); Maple bark stripping; Metal-working fluid mist (machinist's lung); Mushroom workers; Dental ultrasonic cleaning (legionella)
Biological markers: Serum precipitins to suspected antigen; BAL lymphocytosis; HRCT (ground glass, head cheese, centrilobular nodules)
NIOSH: NIOSH WoRLD HP; NIOSH HHE for cluster investigation
Notification: OSHA 300; state WC; NIOSH HHE
Bronchiolitis obliterans ('popcorn lung'); obstructive lung disease
ICD-10-CM J44.0 · J84.89
Key exposures: Microwave popcorn manufacture (flavoring application); Flavoring manufacture; Coffee roasting and grinding (diacetyl natural); E-cigarette / vape juice production (legacy concern)
Biological markers: Serial spirometry (fixed obstruction); HRCT mosaic attenuation
NIOSH: NIOSH Criteria Document 2016
Notification: OSHA 300; state WC; NIOSH HHE
Metal fume fever (acute zinc oxide), siderosis, COPD, increased pneumonia susceptibility (welder's pneumonia)
ICD-10-CM T59.91XA · J92.9 · J44.9
Key exposures: All welding processes — particularly stainless (Cr/Ni/Mn fume), galvanized (Zn), aluminum, magnesium
Biological markers: Substance-specific where applicable; Chest X-ray (siderosis benign opacities)
Notification: OSHA 300; state WC
WTC cough, RADS, sinusitis, GERD, ILD, chronic rhinosinusitis, post-traumatic stress co-morbidity
ICD-10-CM J45.998 · K21.9 · J84.9 · J32.9 · F43.10
Key exposures: First responders Sept 11 2001; Recovery and cleanup workers; Lower Manhattan residents and workers (survivors)
Biological markers: WTC Health Program annual exam (CT chest, PFT, mental health screen)
Notification: WTC Health Program enrollment (Zadroga Act); does NOT require state WC
Allergic contact dermatitis (ACD)
ICD-10-CM L23.0-L23.9
Key exposures: Healthcare (gloves — accelerators not latex post-2010); Hairdressing (PPD, persulfates, fragrances); Construction (chromate in cement, epoxy resins); Metal work (nickel, cobalt); Cleaning (preservatives, fragrance)
Biological markers: Patch testing T.R.U.E. test or extended series (gold standard for diagnosis)
NIOSH: BLS SOII skin disorders; state SENSOR-Dermatitis (CA, MA, NJ, NY)
Notification: OSHA 300 M(1); state WC
Irritant contact dermatitis (ICD)
ICD-10-CM L24.0-L24.9
Key exposures: Wet work (healthcare, food service, hairdressing); Solvents; Detergents and disinfectants; Cement (alkaline); Acids and alkalis
Biological markers: Negative patch testing; clinical correlation; symptom-exposure-improvement diary
Notification: OSHA 300 M(1); state WC
Chloracne from PCB/PCDD/PCDF exposure
ICD-10-CM L70.8
Key exposures: PCB/dioxin manufacture (legacy); Industrial accidents (Seveso, Yusho, Yu-cheng); Herbicide manufacture (TCDD trace contamination — Agent Orange historical); Transformer servicing pre-1979
Biological markers: Adipose tissue PCB/dioxin (research only)
Notification: OSHA 300; state WC; VA Agent Orange registry if veteran
Alkali chemical burns from prolonged skin contact with wet cement
ICD-10-CM T26.5XXA · L24.7
Key exposures: Construction concrete workers (especially knee contact, deep burns)
Biological markers: Clinical
Notification: OSHA 300; state WC
Cutaneous BCC and SCC in outdoor workers (face, neck, dorsal hands)
ICD-10-CM C44.x
Key exposures: Construction (especially roofers); Agriculture; Postal carriers; Park rangers / forestry; Maritime
Biological markers: Total skin exam annually for high-exposure outdoor workers (ACOEM consensus)
Notification: Cancer registries (SEER for tracked sites); state WC (rare claim approval); some state presumption laws emerging
Malignant pleural mesothelioma; malignant peritoneal mesothelioma; malignant pericardial / tunica vaginalis mesothelioma
ICD-10-CM C45.0 · C45.1 · C45.2
Key exposures: See asbestos exposure list (4A02); even very low exposures associated with mesothelioma; latency 20-50 years
IARC: Group 1 — asbestos all forms (since 1977/2012 reaffirmation)
Biological markers: Pleural fluid cytology + cell block (calretinin, podoplanin, WT-1, mesothelin); Pleural biopsy with immunohistochemistry
Notification: OSHA 300; state WC; state cancer registries (SEER); 9/11 WTCHP if eligible; OWCP if federal worker
Lung cancer attributable to occupational exposure
ICD-10-CM C34.x
Key exposures: Asbestos (all subtypes; synergistic with smoking ~50x); Crystalline silica (IARC 1 since 1997); Cr(VI) (IARC 1); Nickel refining (IARC 1); Arsenic (IARC 1); Cadmium (IARC 1); Beryllium (IARC 1); Diesel engine exhaust (IARC 1 since 2012); Bis(chloromethyl) ether (BCME); Hardwood dust (sinonasal; lung weaker); Plutonium (IARC 1); Radon (uranium mining; also residential); Tobacco smoke + occupational combined risk
IARC: Multiple Group 1 agents
Biological markers: LDCT lung screening for eligible (USPSTF B 50-80, >=20 pack-years)
Notification: OSHA 300; state WC; state cancer registries; WTCHP if 9/11
Urothelial carcinoma of bladder from occupational aromatic amine exposure
ICD-10-CM C67.x
Key exposures: Benzidine and benzidine-based dyes (largely banned); 2-Naphthylamine (banned 1977 OSHA); 4-Aminobiphenyl (banned); Auramine production; MOCA — 4,4'-methylenebis(2-chloroaniline); Rubber industry (legacy aromatic amine exposure); Dye manufacture; Aluminum production
IARC: Group 1 — multiple aromatic amines
Biological markers: Urine cytology screening in known exposed (limited sensitivity)
Notification: OSHA 300; state WC; SEER
Acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), non-Hodgkin lymphoma
ICD-10-CM C92.0 · C92.9 · D46.9 · C85.9
Key exposures: Benzene (AML, MDS — IARC 1); Ethylene oxide (NHL, AML, breast cancer — IARC 1); Formaldehyde (myeloid leukemia, NPC — IARC 1); 1,3-Butadiene (CML — IARC 1)
Biological markers: CBC surveillance; t(9;22) and other cytogenetics in established cases
Notification: OSHA 300; state WC; SEER
Sinonasal adenocarcinoma + SCC
ICD-10-CM C30.0 · C31.x
Key exposures: Hardwood dust (IARC 1) — furniture, cabinetry; Leather dust (boot/shoe making — historical); Nickel (IARC 1); Formaldehyde (NPC — IARC 1)
Biological markers: Nasal endoscopy if symptomatic; CT/MRI if mass
Notification: OSHA 300; state WC; SEER
Laryngeal SCC associated with asbestos exposure
ICD-10-CM C32.x
Key exposures: Asbestos — IARC reclassified larynx as causally associated 2012
Notification: OSHA 300; state WC; WTCHP
Hepatic angiosarcoma (rare, near-pathognomonic for occupational VCM exposure)
ICD-10-CM C22.3
Key exposures: PVC monomer manufacture (sealed since OSHA 1974 rule 1910.1017)
IARC: Group 1
Biological markers: LFTs, AFP, imaging if exposure history
Notification: OSHA 300; state WC; SEER
Multiple cancer types causally linked to firefighter exposures (PFAS, combustion byproducts, asbestos in legacy fires, diesel exhaust)
ICD-10-CM C-series various
Key exposures: Structural firefighters; Wildland firefighters; Aircraft rescue firefighters
IARC: Group 1 — Occupation of firefighting (IARC 2022 upgrade from 2A to 1)
Presumption cancers: Bladder cancer, Mesothelioma, Testicular cancer, Kidney cancer, Lung cancer (non-smokers), Multiple myeloma, Non-Hodgkin lymphoma, Leukemia, Brain cancer, Prostate cancer (newer additions), Breast cancer (women firefighters), Colorectal cancer
Notification: State WC presumption claim; state firefighter cancer registry (where exists); WTCHP if 9/11
Radiation-induced leukemia, thyroid, breast, lung, GI cancers
ICD-10-CM C-series
Key exposures: Atomic Veterans / DOE nuclear weapons workers (EEOICPA covered); Uranium miners (Radiation Exposure Compensation Act RECA — reauthorized + expanded Pub L 119-21 §§100201-205 (July 4, 2025); ID/UT/NM downwinders + post-1971 uranium workers + new MPW program MO/KY/TN/AK; filing deadline Dec 31, 2027); Medical/nuclear medicine workers (LSS data); 9/11 cleanup ash exposures
Federal compensation: EEOICPA (Energy Employees Occupational Illness Compensation Program Act) — DOE/AWE site workers, lump-sum + medical; RECA (Radiation Exposure Compensation Act) — atomic veterans, uranium miners, downwinders; VA Agent Orange / Atomic Veterans presumption
Notification: OWCP EEOICPA / RECA; OSHA 300; state WC; VA if veteran
Median nerve compression at the wrist with paresthesia, weakness, nocturnal symptoms
ICD-10-CM G56.00 · G56.01 · G56.02
Key exposures: Repetitive forceful hand exertion (assembly, meat/poultry processing); Sustained pinch grip; Vibrating tools; Awkward wrist posture (data entry — less consistent evidence)
Biological markers: Nerve conduction study (gold standard); Phalen, Tinel, Durkan compression tests
NIOSH: BLS SOII MSD; California SENSOR-CTS surveillance
Notification: OSHA 300 M(5); state WC
Rotator cuff tendinopathy, partial- and full-thickness tears
ICD-10-CM M75.1x · M75.4x
Key exposures: Overhead work (construction, electricians, painters); Repetitive shoulder work (manufacturing assembly); Heavy lifting
Biological markers: Physical exam (Neer, Hawkins, painful arc); MRI if surgical consideration
Notification: OSHA 300 M(5); state WC
Lateral epicondylitis ('tennis elbow'), medial epicondylitis ('golfer's elbow')
ICD-10-CM M77.1x · M77.0x
Key exposures: Repetitive forceful gripping with extended wrist; Plumbers, carpenters, butchers, electricians
Biological markers: Cozen's test; Mill's test; pain on resisted wrist extension
Notification: OSHA 300; state WC
Low back pain with mechanical or radicular features; herniated lumbar disc with radiculopathy
ICD-10-CM M54.5x · M51.16 · M51.17
Key exposures: Manual material handling (warehouse, healthcare patient handling); Whole body vibration (truck drivers, heavy equipment); Prolonged static postures (sitting and standing)
Biological markers: MRI lumbar if red flags or surgical consideration; EMG if radiculopathy
NIOSH: BLS SOII back injuries leading category of WMSD lost-time
Notification: OSHA 300 M(5); state WC
Work-related low back and shoulder injuries in healthcare from patient handling
ICD-10-CM M54.5x · M75.1x
Key exposures: Nurses, nursing aides, physical therapists, EMS
NIOSH: NIOSH safe patient handling: lifting >35 lbs of patient weight requires mechanical assist
Notification: OSHA 300; state WC
State overlays: 11+ states have safe patient handling laws (CA, IL, NY, etc.)
Post-traumatic stress disorder from occupational critical incidents
ICD-10-CM F43.10 · F43.11 · F43.12
Key exposures: Firefighters; EMS personnel; Police officers; Corrections officers; Dispatchers (911 telecommunicators); Emergency department staff; Combat veterans (VA jurisdiction)
Biological markers: PCL-5 (PTSD Checklist DSM-5); CAPS-5 if clinician-administered
Notification: State WC; many states have presumption laws (see overlays); EAP referral standard
Physical injury or acute stress reaction from workplace violence (Type I criminal, Type II customer/client, Type III worker-on-worker, Type IV personal relationship)
ICD-10-CM Y07.x · T74.x · F43.0 · F43.10
Key exposures: Healthcare (Type II most common — ED, psych, long-term care); Retail/convenience store (Type I robbery); Social services (Type II); Education (multiple types); Public-facing roles
Biological markers: Acute stress disorder screening if traumatic event
Notification: OSHA 300; OSHA 1904.39 if hospitalization/fatality; state WC; law enforcement if criminal
Burnout syndrome (emotional exhaustion, depersonalization, low personal accomplishment); secondary traumatic stress; second victim phenomenon
ICD-10-CM Z73.0 · F43.8
Key exposures: Healthcare (HCP burnout heightened post-COVID); EMS and first responders; Teachers (rising 2020-2026); Mental health professionals; Social workers
Biological markers: Copenhagen Burnout Inventory (CBI) — preferred public domain; Maslach Burnout Inventory (MBI) — Mind Garden copyright (avoid for SEED)
Notification: Rarely OSHA 300 (recordability disputed); state WC (rare approval); EAP / wellness program; ACGME wellness for residents
Carve-outs that run outside the state workers'-comp system, with their own eligibility and benefits.
WTCHP
World Trade Center Health Program — federally-funded monitoring and treatment for 9/11 responders and survivors under the James Zadroga 9/11 Health and Compensation Act.
James Zadroga 9/11 Health and Compensation Act →EEOICPA
Energy Employees Occupational Illness Compensation Program Act — lump-sum + medical benefits for DOE nuclear-weapons / energy workers (paired with the DOE Former Worker screening program).
EEOICPA + DOE FWP →Black Lung Benefits Act
Coal-miner pneumoconiosis benefits administered by the OWCP (Office of Workers' Compensation Programs), separate from state systems.
30 USC §901 et seq. →50-state workers'-comp presumption laws
Workers' comp presumption laws shift the burden of proof: instead of the worker proving work causation, the disease is PRESUMED work-related for covered occupations unless the employer/insurer rebuts. Most common categories: firefighter cancer (~48 states with some form), first responder PTSD (~30 states), heart-lung (FF and LEO, ~40 states), COVID-19 essential worker (most states had emergency presumptions 2020-2022, many sunsetted or restricted).
State variation is the rule, not the exception. Firefighter cancer, first-responder PTSD and heart-lung presumptions differ in scope and covered conditions across states (e.g. CA, NY, TX). Flag: state variation — see the specific state workers' compensation commission.
Coding cross-reference — how diseases are catalogued
| Dimension | 🇺🇸 US | 🇬🇧 UK | 🇪🇸 ES |
|---|---|---|---|
| Closed legal list | None (synthesis) | IIDB PD A1–D12 | RD 1299/2006 |
| Coding scheme | ICD-10-CM + Y96/Z57.x | PD lettered codes | RD grupos 1–6 |
| Recording | OSHA 300 columns M(1)–M(5) | RIDDOR report to HSE | CEPROSS / parte EP |
| Compensation | 50-state WC + federal carve-outs | IIDB (centralized DWP) | Seguridad Social (centralized) |
US uses ICD-10-CM diagnostic codes plus Y96 (work environment) and Z57.x (occupational exposure) external-cause codes — there are no US-specific lettered disease codes as in the UK PD scheme or numbered groups as in ES RD 1299/2006.
Under the physician's clinical judgement
Si detectas un error clinico, una dosis sospechosa o quieres sugerir una mejora. No incluyas datos identificables del paciente en el cuerpo del email, por favor.
Adjuntamos URL + version automaticamente. Tu email queda gestionado por tu cliente local. xOH no recibe ni almacena nada.