🇺🇸 United States 🇺🇸 United States · BLS SOII · OSHA recordkeeping 1904 · NIOSH surveillance

Occupational disease catalogue

There is no unified federal occupational-disease list in the US — unlike the UK's IIDB Prescribed Diseases (PD A1–D12) or Spain's closed-list RD 1299/2006. This catalogue is a synthesis of 70 occupational diseases built from BLS SOII + OSHA 29 CFR 1904 recordkeeping + NIOSH surveillance, bound to ICD-10-CM codes and 50-state workers'-compensation presumption variation.

chemical: 20physical: 6biological: 11pneumoconioses asthma hp: 11skin: 5cancer: 9wmsd us specific: 5mental health us specific: 3

No unified federal list — fragmentation is the US characteristic

There is no U.S. federal equivalent to Spain's RD 1299/2006 closed-list catalog. Work-relatedness is determined case-by-case under state workers' compensation laws (50 systems) and OSHA recordkeeping.

This fragmentation is structural, not an anomaly: work-relatedness is decided case-by-case across 50 state workers'-comp systems, layered on OSHA recordkeeping and federal surveillance.

Primary regulatory anchors

The federal surveillance + recordkeeping scaffolding that replaces a single statutory list.

OSHA Recordkeeping Standard

link

29 CFR 1904

Defines work-relatedness (29 CFR 1904.5) and recording criteria (1904.7) for the OSHA 300 log

OSHA Toxic and Hazardous Substances

link

29 CFR 1910 Subpart Z

Substance-specific PELs and surveillance triggers

OSHA Bloodborne Pathogens Standard

link

29 CFR 1910.1030

BBP HBV/HCV/HIV exposures

BLS Survey of Occupational Injuries and Illnesses

link

Bureau of Labor Statistics SOII

Annual surveillance; 7 illness categories on Form 300

NIOSH Work-Related Lung Disease (WoRLD) Surveillance System

link

NIOSH WoRLD

Surveillance of asbestos, coal, silica, beryllium, asthma, HP

ICD-10-CM External Cause Codes

link

Y96 (Work environment), Z57.x (Occupational exposure)

Diagnostic coding for occupational nature

World Trade Center Health Program (Zadroga Act)

link

James Zadroga 9/11 Health and Compensation Act

Federally-funded health monitoring for 9/11 responders/survivors

Department of Energy Former Worker Medical Surveillance Program (FWP)

link

EEOICPA + DOE FWP

DOE nuclear weapons / energy workers

Black Lung Benefits Act

link

30 USC §901 et seq.

Coal miner pneumoconiosis benefits administered by OWCP

OSHA Form 300 — illness columns

  • M(1) Skin disorder
  • M(2) Respiratory condition
  • M(3) Poisoning
  • M(4) Hearing loss
  • M(5) All other illnesses

29 CFR 1904 records work-related cases but does NOT enumerate diseases.

Default notification pathways

  • Employer OSHA 300/300A/301 if recordable per 29 CFR 1904.7
  • BLS SOII annual survey response (sampled employers only)
  • State workers' compensation claim filing (employee-initiated; state-specific timelines)
  • CDC NNDSS / state public health if reportable infectious disease
  • NIOSH HHE (Health Hazard Evaluation) request — employer or employee may initiate
  • OSHA Severe Injury Reporting (1904.39): in-patient hospitalization within 24 hours; amputations and eye loss within 24 hours; fatalities within 8 hours
Group 1 — Diseases caused by chemical agents 20 entries
1A01

Arsenic and inorganic compounds

1A METALS
M(3) Poisoning

Arsenicism (chronic): peripheral neuropathy, dyskeratosis, hyperpigmentation, anemia; lung/skin/bladder cancer in Group 6

OSHA PEL 10 ug/m3 TWA (29 CFR 1910.1018) NIOSH REL C 2 ug/m3 15-min ceiling

ICD-10-CM T57.0X1A · T57.0X4A · Z57.4 · Z77.018

Key exposures: Smelting of copper, lead, zinc with arsenic-containing ores; Semiconductor (GaAs) manufacturing; Pesticide / herbicide / wood preservative manufacture (CCA, MSMA); Glass industry decolorization; Coal-fired power plant cleanup; Mining of arsenic-bearing ores

Biological markers: Urinary arsenic (sum of inorganic + monomethyl + dimethyl species) — BEI 35 ug/L (referenced; ACGIH copyright); Hair/nail arsenic — environmental indicator only, not biological monitoring

NIOSH: ABLES (focused on lead but ABLES network used for some As cluster investigations); NHANES population reference

Notification: OSHA 300 M(3); state WC; CDC NIOSH consultation if cluster

1A02

Beryllium and compounds

1A METALS
M(2) Respiratory

Chronic Beryllium Disease (CBD), beryllium sensitization (BeS), acute beryllium pneumonitis

OSHA PEL 0.2 ug/m3 TWA + 2 ug/m3 STEL (29 CFR 1910.1024 — updated 2017) NIOSH REL 0.05 ug/m3 ceiling 15-min

ICD-10-CM J63.2 · Z57.5 · T56.7X1A

Key exposures: Beryllium machining (aerospace, electronics); Nuclear weapons component manufacture (DOE sites); Dental laboratory work with Be alloys; Ceramics manufacture; Metal recycling

Biological markers: Beryllium Lymphocyte Proliferation Test (BeLPT) — definitive screen for sensitization

NIOSH: DOE FWP includes BeLPT; CBD listed in NIOSH WoRLD pneumoconiosis category

Notification: OSHA 300 M(2); DOE FWP if DOE-related; state WC; EEOICPA claim if DOE/AWE site exposure

1A03

Cadmium and compounds

1A METALS
M(2) Respiratory or M(3) Poisoning

Cadmium nephropathy (tubular proteinuria), pulmonary disease (acute pneumonitis, chronic), itai-itai-like osteomalacia; lung/prostate cancer in Group 6

OSHA PEL 5 ug/m3 TWA (29 CFR 1910.1027) NIOSH REL Lowest feasible concentration (carcinogen)

ICD-10-CM N14.3 · J68.0 · T56.3X1A

Key exposures: Battery manufacture (NiCd); Electroplating; Pigment manufacture (CdS, CdSe); Brazing/soldering with Cd-containing alloys; PVC stabilizer manufacture; Solar cell (CdTe) manufacture; Smelting/refining of zinc, lead, copper

Biological markers: Cadmium in blood (CdB) — recent exposure; Cadmium in urine (CdU) — body burden, normalize to creatinine; Beta-2-microglobulin in urine — early renal effect; Retinol-binding protein urine

NIOSH: Cadmium monitoring required by OSHA 1910.1027 for exposed workers

Notification: OSHA 300; state WC

1A04

Chromium VI (hexavalent)

1A METALS
M(2) Respiratory or M(1) Skin

Cr(VI) ulcerations (nasal septum perforation), allergic contact dermatitis, asthma; sinonasal/lung cancer in Group 6

OSHA PEL 5 ug/m3 TWA (29 CFR 1910.1026 — 2006 standard) NIOSH REL 0.2 ug/m3 TWA

ICD-10-CM J68.2 · J30.81 · L23.0 · T56.2X1A

Key exposures: Electroplating (hard chrome); Stainless steel welding (especially MIG/MMA); Leather tanning; Chromate pigment manufacture; Wood preservation (CCA); Cement and concrete (trace Cr(VI))

Biological markers: Urinary chromium end-of-shift end-of-workweek

NIOSH: OSHA medical surveillance if exposure >=action level (2.5 ug/m3)

Notification: OSHA 300; state WC

1A05

Lead (inorganic, Pb)

1A METALS
M(3) Poisoning

Plumbism: peripheral neuropathy, encephalopathy, anemia (microcytic/hypochromic), nephropathy, hypertension, reproductive effects, lead colic

OSHA PEL 50 ug/m3 TWA general industry (29 CFR 1910.1025) — under revision; Cal/OSHA tightened 2024 to 10 ug/m3 NIOSH REL <=50 ug/m3 TWA but recommends much lower

ICD-10-CM T56.0X1A · T56.0X4A · G62.2

Key exposures: Battery manufacture and recycling; Lead smelting/refining; Construction trades — abrasive blasting, demolition, welding of painted steel; Firing ranges (commercial and indoor); Radiator repair (legacy); Pottery and stained glass (legacy); Bridge / steel structure painting / abatement; Ammunition manufacture; Lead-based paint abatement

Biological markers: Blood lead level (BLL) — primary surveillance test; Zinc protoporphyrin (ZPP); ALA-D erythrocyte (research); Urinary lead — limited utility

Medical removal: OSHA general industry: BLL >=60 ug/dL (or 3 consecutive >=50). Construction: >=50 (or 3 >=40). NIOSH/CDC ABLES recommends action at BLL >=5 ug/dL. CDC CDC adult reference BLL is <3.5 ug/dL (2021 update from 5).

NIOSH: ABLES (Adult Blood Lead Epidemiology and Surveillance) — CDC funded in ~30 states

Notification: OSHA 300 M(3); state ABLES program; state WC

State workers'-comp overlays (3)
  • US-CA — Cal/OSHA PEL lowered to 10 ug/m3 TWA; action level 2 ug/m3; medical removal at BLL >=20 ug/dL; mandatory BLL testing at lower thresholds Cal/OSHA 8 CCR 5198 final rule (Standards Board approved Feb 15, 2024; effective Jan 1, 2025) · applies when: employer in California
  • US-NY — Mandatory BLL reporting by labs >=5 ug/dL adults; state surveillance follow-up NY ABLES program (NYSDOH) · applies when: lab in NY
  • US-MI — Enhanced lead surveillance for Flint exposure cohort; MDHHS coordination; pediatric BLL surveillance separate from adult occupational. Adult occupational lead surveillance follows OSHA 1910.1025; Flint-specific public health follow-up overlaps MI Flint Water Crisis (2014-present) + MDHHS lead surveillance · applies when: MI worker or resident with Flint exposure history (occupational + environmental overlap)
1A06

Mercury (elemental, inorganic, organic)

1A METALS
M(3) Poisoning

Mercurialism: erethism, tremor, gingivitis (elemental); methylmercury — neurologic (cerebellar/visual); inorganic — nephropathy; acrodynia (children)

OSHA PEL 0.1 mg/m3 ceiling for organomercury; 0.05 mg/m3 vapor TWA (Subpart Z) NIOSH REL 0.05 mg/m3 TWA vapor

ICD-10-CM T56.1X1A · G62.2 · N14.3

Key exposures: Dental amalgam preparation (legacy and current low-level); Thermometer/barometer manufacture (legacy); Chlor-alkali plants (largely closed by 2013); Gold mining (artisanal — DOE/state cleanup workers); Fluorescent lamp recycling; Mining of cinnabar (legacy); Hg-containing waste disposal

Biological markers: Urinary mercury (Hg-U) — body burden inorganic + elemental; Blood mercury (Hg-B) — methylmercury preferred

NIOSH: Some state biomonitoring programs

Notification: OSHA 300; state WC; CDC NCHS NHANES population reference

1A07

Manganese

1A METALS
M(3) Poisoning

Manganism: parkinsonian syndrome (resting tremor less prominent than idiopathic PD; gait disturbance and cock-walk; psychiatric prodrome)

OSHA PEL 5 mg/m3 ceiling fume (Subpart Z) NIOSH REL 1 mg/m3 TWA + 3 mg/m3 STEL

ICD-10-CM T57.2X1A · G21.8

Key exposures: Welding (especially of mild and stainless steel — fume contains Mn); Dry battery manufacture; Ferromanganese alloy production; Mn ore mining and milling; Welder's grinding

Biological markers: Blood Mn (limited specificity); MRI brain T1-weighted globus pallidus hyperintensity (biological effect, not biomarker proper)

NIOSH: Welding fume surveillance under multiple substance-specific NIOSH bulletins

Notification: OSHA 300; state WC

1A08

Nickel (sensitization)

1A METALS
M(1) Skin or M(2) Respiratory

Nickel allergic contact dermatitis; respiratory sensitization. (Nickel refining / inhaled compound carcinogens in Group 6)

OSHA PEL 1 mg/m3 TWA (metal and soluble compounds) NIOSH REL 0.015 mg/m3 TWA (carcinogen)

ICD-10-CM L23.0 · J45.998 · T56.891A

Key exposures: Nickel plating; Stainless steel manufacture and welding; Coin handling (cashiers — non-occupational mostly); Jewelry making; Battery manufacture (NiCd, NiMH)

Biological markers: Patch testing for sensitization (clinical, not surveillance)

Notification: OSHA 300; state WC

1B01

Benzene

1B ORGANIC SOLVENTS — AROMATIC
M(3) Poisoning or M(2)

Aplastic anemia, myelodysplastic syndrome, pancytopenia. (Acute leukemia in Group 6.)

OSHA PEL 1 ppm TWA + 5 ppm STEL (29 CFR 1910.1028) NIOSH REL 0.1 ppm TWA + 1 ppm 60-min ceiling (carcinogen)

ICD-10-CM D61.2 · T52.1X1A · Z57.5

Key exposures: Petroleum refining (BTX recovery); Coke oven operations; Rubber manufacturing; Solvent use in industry (largely phased out as bulk solvent); Gasoline distribution and retail (low-level); Chemical manufacture using benzene intermediates

Biological markers: Urinary trans,trans-muconic acid (ttMA); Urinary S-phenylmercapturic acid (S-PMA) — more specific

NIOSH: OSHA 1910.1028 medical surveillance required >=action level

Notification: OSHA 300; state WC

1B02

Toluene

1B ORGANIC SOLVENTS — AROMATIC
M(3) Poisoning

Toluene encephalopathy (chronic — cognitive decline, cerebellar dysfunction), acute CNS depression, ototoxicity (synergistic with noise)

OSHA PEL 200 ppm TWA + 300 ppm ceiling + 500 ppm max peak (Subpart Z) NIOSH REL 100 ppm TWA + 150 ppm STEL

ICD-10-CM G92 · T52.2X1A · H93.099

Key exposures: Paint and lacquer manufacture and application; Adhesive manufacture (especially in shoe and leather); Printing; Solvent abuse occupational settings (rare but documented); Toluene-based degreasing

Biological markers: Urinary o-cresol — preferred specific; Urinary hippuric acid — non-specific (also from food)

Ototoxicity: NIOSH ototoxicity flag — toluene exposure synergizes with noise; consider co-surveillance audiometry

Notification: OSHA 300; state WC

1B03

Styrene

1B ORGANIC SOLVENTS — AROMATIC
M(3) Poisoning

Styrene encephalopathy, ototoxicity, reproductive effects. (Probable carcinogen IARC 2B — group 6 if confirmed.)

OSHA PEL 100 ppm TWA + 200 ppm ceiling + 600 ppm peak (Subpart Z) NIOSH REL 50 ppm TWA + 100 ppm STEL

ICD-10-CM G92 · T52.4X1A

Key exposures: Glass fiber-reinforced plastic (GFRP) lay-up (boat, bathtub, automotive parts); Polystyrene manufacturing; Synthetic rubber (SBR) production; Resin and composite work

Biological markers: Urinary mandelic acid + phenylglyoxylic acid (end-of-shift)

Notification: OSHA 300; state WC

1C01

n-Hexane

1C ORGANIC SOLVENTS — ALIPHATIC
M(3) Poisoning

Distal symmetric sensorimotor axonal polyneuropathy (legs first, ascending). Visual impairment in severe cases.

OSHA PEL 500 ppm TWA (Subpart Z — outdated) NIOSH REL 50 ppm TWA

ICD-10-CM G62.2 · T52.0X1A

Key exposures: Shoe and leather adhesive manufacture; Furniture finishing; Printing solvent; Vegetable oil extraction (refineries); Auto repair shop solvent use

Biological markers: Urinary 2,5-hexanedione (end-of-shift, end-of-workweek)

Notification: OSHA 300; state WC

1C02

Methylene chloride (dichloromethane, DCM)

1C ORGANIC SOLVENTS — ALIPHATIC
M(3) Poisoning

Acute CNS depression, COHb elevation (metabolism to CO), hepatic effects. Banned from consumer paint stripper 2019. (IARC 2A; cancer in Group 6.)

OSHA PEL 25 ppm TWA + 125 ppm STEL (29 CFR 1910.1052) NIOSH REL Lowest feasible (carcinogen)

ICD-10-CM T53.4X1A · G92

Key exposures: Paint stripping (commercial only as of EPA 2019 rule); Pharmaceutical manufacture; Adhesive and aerosol manufacture; Plastics processing

Biological markers: COHb at end-of-shift; Urinary DCM

Notification: OSHA 300; state WC; EPA reporting for commercial paint strip

1C03

Trichloroethylene (TCE)

1C ORGANIC SOLVENTS — CHLORINATED
M(3) Poisoning

Liver injury, renal effects, dermatitis. IARC Group 1 — kidney cancer in Group 6.

OSHA PEL 100 ppm TWA + 200 ppm ceiling + 300 ppm peak (Subpart Z) NIOSH REL Lowest feasible (carcinogen)

ICD-10-CM K71.3 · T53.2X1A

Key exposures: Metal degreasing (largely phased out post-2000 in U.S.); Solvent in adhesives; Dry cleaning (PCE/perc primarily but TCE secondary); Aerospace cleaning operations

Biological markers: Urinary trichloroacetic acid (TCA); Urinary trichloroethanol

Notification: OSHA 300; state WC; EPA TSCA risk evaluation 2020 -- restrictions advancing

1D01

Formaldehyde (HCHO)

1D FORMALDEHYDE & ALDEHYDES
M(2) Respiratory or M(1) Skin

Irritant contact dermatitis, asthma, allergic contact dermatitis. IARC Group 1 — nasopharyngeal cancer + myeloid leukemia in Group 6.

OSHA PEL 0.75 ppm TWA + 2 ppm STEL (29 CFR 1910.1048) NIOSH REL 0.016 ppm TWA + 0.1 ppm ceiling 15-min (carcinogen)

ICD-10-CM L23.5 · J68.3 · T59.2X1A

Key exposures: Anatomy / pathology laboratories (embalming, tissue fixation); Mortuary work; Particle board / plywood / OSB manufacture; Textile finishing (permanent press); Foundry core-making (phenol-formaldehyde resin)

Biological markers: No reliable biomarker; environmental measurement primary

Notification: OSHA 300; state WC

1D02

Glutaraldehyde

1D FORMALDEHYDE & ALDEHYDES
M(2) or M(1)

Occupational asthma, allergic contact dermatitis, irritant contact dermatitis, conjunctivitis

OSHA PEL None federal — ACGIH TLV 0.05 ppm ceiling (referenced; copyright) NIOSH REL 0.2 ppm ceiling

ICD-10-CM J45.998 · L23.5 · H10.45

Key exposures: High-level disinfection of endoscopes / instruments in healthcare; Cold sterilization solutions; X-ray film developing (legacy); Embalming

Biological markers: None standardized

Notification: OSHA 300; state WC

1E01

Diisocyanates (TDI, MDI, HDI)

1E ISOCYANATES
M(2) Respiratory

Occupational asthma (LMW sensitizer), hypersensitivity pneumonitis, allergic rhinitis, contact dermatitis

OSHA PEL TDI 0.02 ppm ceiling; HDI/MDI fall under general dust/mist NIOSH REL 0.005 ppm TWA + 0.02 ppm 10-min ceiling (TDI)

ICD-10-CM J45.998 · J67.8 · J30.81

Key exposures: Polyurethane foam manufacture (rigid and flexible); Spray-applied polyurethane insulation (SPF); Automotive painting (urethane clear coats); Adhesive manufacture; Coatings application; Cast-elastomer manufacture

Biological markers: Urinary TDA / MDA (diamine metabolites); Specific IgE / IgG antibody (limited clinical)

NIOSH: Spray polyurethane foam industry HHEs

Notification: OSHA 300; state WC

1F01

Carbon monoxide (CO)

1F OXIDES
M(3) Poisoning

Acute CO poisoning (hypoxic encephalopathy), chronic neuropsychiatric sequelae

OSHA PEL 50 ppm TWA (Subpart Z) NIOSH REL 35 ppm TWA + 200 ppm ceiling

ICD-10-CM T58.01XA · T58.91XA · G93.41

Key exposures: Indoor use of fuel-powered equipment (forklifts, generators, pressure washers); Firefighting (smoke inhalation); Auto repair (running engines indoors); Charcoal production; Iron and steel foundry / blast furnace; Mining

Biological markers: Carboxyhemoglobin (COHb) — venous or arterial; SpCO via co-oximetry; Reference: nonsmoker <2%, smoker <10%

Notification: OSHA 300; state WC; OSHA 1904.39 reporting if hospitalization

1F02

Hydrogen sulfide (H2S)

1F OXIDES
M(3) Poisoning

Acute H2S poisoning (knockdown / respiratory paralysis), chronic neurocognitive effects, ocular irritation (keratoconjunctivitis 'gas eye')

OSHA PEL 20 ppm ceiling + 50 ppm peak 10-min once per shift (Subpart Z) NIOSH REL 10 ppm ceiling 10-min

ICD-10-CM T59.6X1A · G92

Key exposures: Oil and gas extraction (sour crude); Confined space entry — sewers, manholes, tanks; Pulp and paper kraft mill; Hog/swine manure pits (lethal incidents documented); Hot springs work; Rendering plants; Tannery work

Biological markers: Urinary thiosulfate (acute, post-exposure)

Notification: OSHA 300; OSHA 1904.39 (fatalities common); state WC

1G01

Organophosphate and carbamate pesticides (cholinesterase inhibitors)

1G PESTICIDES
M(3) Poisoning

Acute cholinergic syndrome (SLUDGE/Killer B's), intermediate syndrome, OPIDN (organophosphate-induced delayed polyneuropathy)

OSHA PEL Substance-specific; EPA WPS (Worker Protection Standard 40 CFR 170) is primary regulatory hook NIOSH REL Substance-specific

ICD-10-CM T60.0X1A · T60.0X4A · G62.2

Key exposures: Agricultural pesticide application (chlorpyrifos restricted in food crops 2021 EPA, partially reinstated 2024); Vector control (mosquito spraying — malathion); Greenhouse work; Veterinary use (livestock dipping — legacy); Termite control (organophosphates restricted)

Biological markers: Erythrocyte acetylcholinesterase (AChE) — baseline pre-season + during season; Plasma butyrylcholinesterase (BuChE) — less specific; Urinary dialkyl phosphates

NIOSH: California SENSOR-Pesticides program; CDC NIOSH pesticide registry

Notification: OSHA 300; state pesticide regulatory authority; EPA WPS; state WC

State workers'-comp overlays (2)
  • US-CA — Mandatory AChE testing for Category I/II OP/Carbamate handlers; mandatory baseline + during season testing protocol CA Code of Regs Title 3 §6728-6739; Cal/OSHA + DPR coordinate · applies when: agricultural pesticide handler in CA
  • US-FL — FDACS enforces EPA WPS; cholinesterase testing voluntary in FL FDACS rules + farmworker WPS · applies when: FL agricultural pesticide handler
Group 2 — Diseases caused by physical agents 6 entries
2A01

Occupational noise (continuous, impact, impulse)

2A NOISE
M(4) Hearing loss (defined: STS + >=25 dB above audiometric zero in averaged 2/3/4 kHz)

Noise-induced hearing loss (sensorineural, bilateral, symmetric, 4 kHz notch initially), tinnitus

OSHA PEL 90 dBA TWA 8-hr (Action level 85 dBA) — 5 dB exchange rate. NIOSH and ACGIH recommend 85 dBA with 3 dB exchange. OSHA std 29 CFR 1910.95 Hearing Conservation Program; 1926.52 Construction noise

ICD-10-CM H83.3 · H93.13 · Z57.0

Key exposures: Construction (heavy equipment, jackhammers); Manufacturing (stamping, grinding); Mining; Agriculture (tractor cabs improved but still risk); Aviation and aerospace (ground crew, military); Music venues, entertainment; Public safety sirens (EMS/police/fire)

Biological markers: Baseline audiogram + annual audiogram; STS (Standard Threshold Shift) = >=10 dB average 2/3/4 kHz

NIOSH: BLS Annual data; NIOSH surveillance NHIS sub-questions

Notification: OSHA 300 M(4) if STS + at-risk + age-correction applied; state WC

2B01

Hand-arm vibration (HAV)

2B VIBRATION
M(5) Other illness

Hand-arm vibration syndrome (HAVS): vascular (Raynaud's phenomenon vibration-induced 'white finger'), neurologic (paresthesias, dexterity loss), musculoskeletal

OSHA PEL None federal — ACGIH TLV referenced (copyright; not included verbatim) NIOSH REL NIOSH 89-106 criteria document references threshold limit values for exposure-response

ICD-10-CM T75.21XA · I73.00

Key exposures: Chainsaw operators (logging, tree care); Grinder / sander / chipper / impact wrench operators; Pneumatic tool use (construction, manufacturing); Jackhammer operators; Dental hygienists (sustained instrument use)

Biological markers: Cold provocation test; Stockholm Workshop Scale classification (vascular + sensorineural)

NIOSH: NIOSH HAV criteria document 1989; no formal national surveillance

Notification: OSHA 300 M(5); state WC

2C01

Ionizing radiation (X-ray, gamma, beta, alpha, neutron)

2C IONIZING RADIATION
M(5) Other or M(2)/M(3) depending on manifestation

Acute radiation syndrome, radiation dermatitis, cataract, hypothyroidism, sterility. Cancer in Group 6.

OSHA std 29 CFR 1910.1096 (general industry); NRC 10 CFR 20 (licensed materials); DOE 10 CFR 835 Limit NRC occupational limit 5 rem (50 mSv)/year whole body; 50 rem lens of eye, 50 rem skin/extremity

ICD-10-CM T66.XXXA · L58.9 · H26.8

Key exposures: Healthcare — interventional radiology, nuclear medicine, radiation oncology; Nuclear power industry; Industrial radiography (NDT); Uranium mining and milling (historical and current); DOE nuclear weapons complex workers; Research labs with radioisotopes

Biological markers: Personal dosimeter (TLD or OSL); Cytogenetic dose reconstruction (lymphocyte chromosomal aberrations) — retrospective

NIOSH: NIOSH-DOE Former Worker Medical Surveillance Program (FWP); SEER linkage for some occupations

Notification: NRC reporting; DOE FWP if DOE-related; OWCP EEOICPA claim for DOE/AWE; state WC

State workers'-comp overlays (1)
  • US-CA — Additional state radioactive material licensing program CDPH Radiologic Health Branch + Cal/OSHA 8 CCR 5074-5104 · applies when: CA-licensed radiologic facility
2D01

Occupational heat exposure

2D HEAT
M(5) Other

Heat exhaustion, heat stroke, heat cramps, heat syncope, rhabdomyolysis, AKI

OSHA std No federal OSHA heat standard (OSHA NPRM 'Heat Injury and Illness Prevention' published August 2024 — finalized 2026 expected). General Duty Clause §5(a)(1) used.

ICD-10-CM T67.0XXA · T67.3XXA · T67.5XXA · M62.82 · N17.9

Key exposures: Outdoor agriculture (especially harvest); Construction (especially roofing, asphalt); Warehouse / parcel delivery (high-profile UPS, Amazon issues); Firefighters (structural and wildland); Foundries, glass, kitchens, laundries; Military training

Biological markers: Core temp (if measured) >=104°F (40°C) = heat stroke; AKI markers; Rhabdo: CK >5x ULN; Acclimatization status

NIOSH: NIOSH Criteria for a Recommended Standard: Occupational Exposure to Heat 2016 update

Notification: OSHA 300 M(5); OSHA 1904.39 if hospitalization or fatality; state WC

State overlays: CA 8 CCR 3395 (outdoor and indoor); OR OAR 437-002-0156; WA WAC 296-307 / 296-62; CO HB22-1248; MN 5205.0110 (indoor)

State workers'-comp overlays (8)
  • US-CA — Mandatory water/shade/rest; written program; high-heat procedures >=95°F; indoor temperatures >=82°F trigger Cal/OSHA Heat Illness Prevention Standard 8 CCR 3395 (outdoor 2005, indoor expanded 2024) · applies when: CA outdoor or indoor workplace meeting threshold
  • US-FL — State law BLOCKS local heat protections; no state OSH program (federal OSHA applies) FL HB 433 (2024) — preempts local heat illness ordinances · applies when: FL workplace
  • US-TX — State law preempts local Austin/Dallas water-break ordinances; no state OSH plan TX HB 2127 (2023) Death Star Act — preempts local heat protections (legal challenges pending) · applies when: TX workplace
  • US-NY — No mandatory standard; federal OSHA + General Duty Clause NYS DOL voluntary guidance; no mandatory state standard · applies when: NY workplace
  • US-OR — Mandatory rest/water/shade above 80°F + acclimatization + emergency response plans + training; applies indoor + outdoor Oregon OSHA OAR 437-002-0156 (Heat Illness Prevention, effective 2022) · applies when: OR outdoor workplace or indoor heat >=80°F
  • US-WA — Mandatory water/shade/rest at ambient >=80°F; mandatory cool-down at >=89°F; mandatory acclimatization WA WAC 296-307 (agriculture) + 296-62 (general industry) Outdoor Heat Exposure (rule updated 2023-2024) · applies when: WA outdoor workplace
  • US-MN — Indoor heat exposure standard — WBGT-based limits; UNIQUE among US states for indoor focus Minnesota Rules 5205.0110 (indoor heat exposure) · applies when: MN indoor workplace meeting WBGT threshold
  • US-CO — Heat illness prevention for agricultural workers (water/shade/rest + acclimatization); narrower scope than CA/OR/WA CO HB22-1248 (2022) — agricultural heat illness prevention · applies when: CO agricultural outdoor worker
2D02

Occupational wildfire smoke exposure (PM2.5 + ozone + CO + VOCs)

2D HEAT
M(2) Respiratory

Acute respiratory irritation, asthma exacerbation, reduced lung function, cardiovascular events; chronic exposure associations under study

OSHA std No federal OSHA wildfire smoke standard; General Duty Clause §5(a)(1); OSHA NPRM Heat (Aug 2024) does not cover smoke. AQI-based intervention per state standards where they exist.

ICD-10-CM J68.3 · J45.901 · J70.8 · R06.02

Key exposures: Wildland firefighters (highest exposure); Outdoor agricultural workers during fire season; Construction + landscaping outdoor workers; Utility + forestry workers; Outdoor workers in fire-prone regions (West Coast, Mountain West, increasingly Canada-smoke-affected Northeast/Midwest)

Biological markers: Spirometry (FEV1/FVC pre/post season); Symptom + AQI exposure diary; Pulse oximetry during exposure

NIOSH: NIOSH wildland firefighter health studies; CDC/ATSDR PM2.5 health tracking

Notification: OSHA 300 M(2) if work-related respiratory; state WC; state air quality program

State workers'-comp overlays (4)
  • US-OR — FIRST comprehensive US state wildfire smoke standard: mandatory respiratory protection + air quality monitoring at AQI >=101 (PM2.5); voluntary respirators at AQI >=51; mandatory training + exposure controls Oregon OSHA OAR 437-002-1080 + 437-004-9000 (Wildfire Smoke rule, 2022) · applies when: OR outdoor workplace during wildfire smoke event
  • US-CA — Mandatory respiratory protection (N95) when AQI for PM2.5 >=151; communication + training requirements; applies when employer should reasonably anticipate exposure Cal/OSHA 8 CCR 5141.1 Protection from Wildfire Smoke (2019, first in nation) · applies when: CA outdoor workplace at AQI >=151
  • US-WA — Mandatory exposure controls + respiratory protection at elevated AQI thresholds; training + response plan WA WAC 296-820 Wildfire Smoke rule (permanent rule effective 2024) · applies when: WA outdoor workplace during wildfire smoke
  • US-AZ — Federal OSHA + ADOSH enforcement under General Duty Clause; no formal state standard AZ ADOSH — no dedicated wildfire smoke standard; General Duty Clause · applies when: AZ outdoor workplace during smoke event
2E01

Hyperbaric/hypobaric exposure

2E PRESSURE
M(5) Other

Decompression sickness (DCS Type I limb pain, Type II neurologic), arterial gas embolism, dysbaric osteonecrosis, barotrauma

OSHA std 29 CFR 1910.401 Subpart T Commercial Diving Operations

ICD-10-CM T70.3XXA · T70.29XA · M87.81

Key exposures: Commercial diving (oil and gas, salvage); Caisson workers (tunneling); Hyperbaric chamber operators (medical hyperbaric); Aviation (high altitude, U-2 pilots); Astronauts

Biological markers: DCI risk indices, dive computer records, Doppler bubble detection

Notification: OSHA 300; state WC; USCG / OSHA Diving Operations reporting

Group 3 — Diseases caused by biological agents 11 entries
3A01

Hepatitis B virus (HBV) — occupational exposure

3A BLOODBORNE
M(5) Other (record bloodborne exposure incident under 1904.8)

Acute and chronic hepatitis B; chronic liver disease; HCC in Group 6

OSHA std 29 CFR 1910.1030 Bloodborne Pathogens — employer must offer HepB vaccine at no cost + post-exposure follow-up

ICD-10-CM B16.9 · B18.1 · Z20.5 · Z57.5

Key exposures: Healthcare workers — needlesticks, splashes; First responders / EMS; Laboratory workers handling blood/tissue; Mortuary workers; Correctional health staff; Tattoo artists / body piercers; Dialysis patients and staff

Biological markers: HBsAg, anti-HBs (immunity post-vaccine >=10 mIU/mL), anti-HBc (past infection), HBeAg, HBV DNA (replication)

Post-exposure: Per CDC USPHS PEP guidelines: HBV PEP within 24h; HBIG if non-immune source HBsAg+

Notification: OSHA 300; CDC NNDSS (acute HBV is nationally notifiable); state WC; OSHA Sharps Injury Log mandatory under 1910.1030

State workers'-comp overlays (1)
  • US-CA — Stricter sharps engineering controls + employee selection process Cal/OSHA 8 CCR 5193 (BBP standard with additional sharps + needleless system mandates) · applies when: CA covered employer
3A02

Hepatitis C virus (HCV) — occupational exposure

3A BLOODBORNE
M(5) Other

Acute and chronic hepatitis C; cirrhosis; HCC in Group 6

OSHA std 29 CFR 1910.1030 (no vaccine available)

ICD-10-CM B17.10 · B18.2 · Z20.5

Key exposures: Same as HBV — primary needlestick risk in healthcare; also dialysis, tattoo, BBF exposures

Biological markers: Anti-HCV (seroconversion 1-3 months), HCV RNA (acute or active infection)

Post-exposure: Per CDC: no PEP; serial monitoring anti-HCV + RNA at 0, 3, 6 weeks (or HCV RNA at 3-6 weeks), then anti-HCV at 4-6 months. DAA treatment if seroconversion (95%+ cure).

Notification: OSHA 300; CDC NNDSS (acute HCV nationally notifiable since 2016); state WC

3A03

Human immunodeficiency virus (HIV) — occupational exposure

3A BLOODBORNE
M(5) Other

Acute retroviral syndrome (seroconversion illness), AIDS

OSHA std 29 CFR 1910.1030

ICD-10-CM B20 · Z21 · Z20.6

Key exposures: Healthcare needlestick / mucocutaneous BBF exposure (low risk per exposure ~0.3% percutaneous, ~0.1% mucosal); Research lab with HIV concentrates

Biological markers: 4th gen Ag/Ab combo at 0, 6, 12 weeks post-exposure; HIV RNA if symptomatic seroconversion

Post-exposure: USPHS PEP within 72h (preferably <2h): 3-drug regimen (TDF/FTC + raltegravir or dolutegravir) x 28 days

Notification: OSHA 300; CDC NNDSS (HIV nationally notifiable); state WC

3B01

Mycobacterium tuberculosis (TB) — occupational

3B AIRBORNE / RESPIRATORY
M(5) Other

Latent TB infection (LTBI), active pulmonary TB, extrapulmonary TB

OSHA std OSHA TB Compliance Directive CPL 02-02-078 (1996; respiratory protection 1910.134)

ICD-10-CM A15.0 · A15.9 · Z20.1 · Z57.5

Key exposures: Healthcare personnel (especially correctional, homeless services, ID); Correctional officers; Homeless services personnel; Lab workers handling MTB cultures; First responders responding to congregate settings

Biological markers: IGRA (T-SPOT.TB or QuantiFERON) preferred over TST in BCG-vaccinated; Chest X-ray if positive

Screening: CDC MMWR 2019 (Sosa et al): baseline IGRA at hire for HCP; annual NOT recommended unless ongoing exposure

Notification: OSHA 300; CDC NNDSS (active TB nationally notifiable); state WC; state public health TB control

3B02

Avian influenza A H5N1 (HPAI) — occupational zoonotic

3B AIRBORNE / RESPIRATORY
M(5) Other

Conjunctivitis, mild respiratory illness, severe ARDS in rare cases

ICD-10-CM J09.X9 · Z20.828

Key exposures: Poultry workers (broiler, layer, breeder operations); Dairy workers (US 2024-2026 dairy H5N1 outbreak — first mammalian dairy transmission); Wildlife / wild bird response personnel; Veterinarians and lab personnel

Biological markers: RT-PCR from conjunctival or respiratory swab; Serology (HI or microneutralization)

Post-exposure: Oseltamivir prophylaxis per CDC; PPE per CDC HAI guidance (eye protection critical)

Notification: OSHA 300; CDC HAN; state public health; USDA APHIS for animal cases

State workers'-comp overlays (2)
  • US-CA — Mandatory state reporting + cluster investigation CDPH H5N1 dairy worker investigation 2024-2025 · applies when: CA dairy or poultry worker
  • US-TX — State investigation per CDC guidance TDSHS surveillance protocol · applies when: TX dairy or poultry worker
3C01

Brucella spp.

3C ZOONOTIC
M(5) Other

Brucellosis (undulant fever): fever, sweats, arthralgia, hepatosplenomegaly, endocarditis (severe)

ICD-10-CM A23.9 · Z20.821

Key exposures: Slaughterhouse workers (cattle, swine, goats); Veterinarians, lab workers; Dairy workers (raw milk); Hunters (feral swine — wild Suis brucellosis)

Biological markers: Serology (Brucella agglutination), blood culture, PCR

Notification: OSHA 300; CDC NNDSS; state public health; USDA APHIS animal cases

3C02

Coxiella burnetii (Q fever)

3C ZOONOTIC
M(5) Other

Acute Q fever (pneumonia, hepatitis), chronic Q fever (endocarditis)

ICD-10-CM A78 · Z20.828

Key exposures: Livestock workers (especially small ruminants — sheep/goats parturition); Slaughterhouse personnel; Lab workers (highest risk — Coxiella BSL-3); Veterinarians; Wool/hide handlers

Biological markers: Serology IgM and IgG to phase I and phase II antigens; PCR from blood

Notification: OSHA 300; CDC NNDSS; state public health; military notification (Iraq/Afghanistan veterans)

3C03

Lyme disease (Borrelia burgdorferi)

3C ZOONOTIC
M(5) Other

Early localized (erythema migrans), early disseminated (carditis, neurologic), late (arthritis, post-treatment Lyme)

ICD-10-CM A69.20 · A69.21 · A69.22 · A69.23

Key exposures: Outdoor workers in endemic Northeast/Mid-Atlantic/upper Midwest: forestry, surveying, utility line work, park rangers, landscapers, agricultural

Biological markers: 2-tier serology (ELISA + Western Blot) per CDC; PCR limited

Notification: OSHA 300; state public health (most states reportable); state WC

3C04

Rabies (rhabdovirus)

3C ZOONOTIC
M(5) Other

Acute progressive encephalitis (~100% fatal once symptomatic)

ICD-10-CM A82.9 · Z20.3

Key exposures: Veterinarians and staff; Animal control officers; Wildlife biologists, spelunkers; Lab workers handling rabies virus

Biological markers: Anti-rabies neutralizing antibody titer (>0.5 IU/mL = adequate)

Post-exposure: PEP per ACIP 2022: 2 doses if previously vaccinated; 4 doses + HRIG if not

Notification: OSHA 300; state public health; CDC NNDSS for human cases

3D01

SARS-CoV-2 (COVID-19) — occupational

3D EMERGING / PANDEMIC
M(2) Respiratory or M(5)

Acute COVID-19, post-acute sequelae of SARS-CoV-2 (PASC / Long COVID)

OSHA std OSHA Healthcare ETS (sunset 2022 except recordkeeping); 1910.1030 BBP does not include SARS-CoV-2; General Duty Clause §5(a)(1)

ICD-10-CM U07.1 · U09.9 · Z20.822

Key exposures: Healthcare personnel (highest risk in early pandemic); Long-term care personnel; Correctional officers; Meatpacking workers (cluster outbreaks 2020); First responders; Public transit personnel; Retail and grocery workers (essential designation)

Biological markers: RT-PCR, antigen test, antibody (post-infection vs post-vaccine differentiation: N protein vs S protein)

Notification: OSHA 300 (per OSHA enforcement memos); CDC NNDSS; state public health; OSHA 1904.39 if hospitalization/fatality work-related

State workers'-comp overlays (3)
  • US-CA — Rebuttable presumption of work-relatedness for COVID-19 in covered occupations EXPIRED effective January 1, 2024 — no new claims under SB 1159 presumption after that date. Pre-2024 claims continue. AB 685 notification obligations separate and ongoing. CA SB 1159 (2020, original sunset Jan 1, 2023; AB 1751 (2022) extended sunset to Jan 1, 2024); AB 685 (2020) employer notification (not WC presumption, ongoing) · applies when: CA worker — historical (pre-2024) claims
  • US-NY — HERO Act COVID-19 airborne infectious disease designation ended March 17, 2022 — no current obligation to enforce COVID exposure prevention plans. HERO Act framework remains for future airborne infectious disease designations. WC presumptions for HCP/first responders varied 2020-2022. NY HERO Act 2021 (signed May 5, 2021; COVID-19 designation Sept 6, 2021); designation ENDED March 17, 2022 · applies when: NY worker — historical (pre-March 2022) claims under HERO designation
  • US-IL — Rebuttable presumption for essential workers covered March-December 2020 (initial diagnosis dates); subsequently restricted by HB 4276 (2021) to first responders + frontline essential workers; presumption sunset by 2022. IL HB 2455 (2020) workers' comp COVID-19 presumption · applies when: IL essential worker — historical (2020-2021) claims
3D02

Mpox (monkeypox virus, MPXV)

3D EMERGING / PANDEMIC
M(5) Other

Mpox: vesiculopustular rash, lymphadenopathy, fever

ICD-10-CM B04 · Z20.828

Key exposures: Healthcare personnel caring for mpox patients; Laboratory personnel handling MPXV; Veterinarians (mpox in mammalian hosts); Public health investigators

Biological markers: MPXV PCR from lesion swab; orthopoxvirus IgG

Post-exposure: JYNNEOS PEP within 4 days (ideally) to 14 days post-exposure

Notification: OSHA 300; CDC NNDSS (mpox nationally notifiable 2022); state public health

Group 4 — Diseases caused by inhalation of substances not classified elsewhere (pneumoconioses, occupational asthma, HP) 11 entries
4A01

Silica (respirable crystalline)

4A PNEUMOCONIOSES
M(2) Respiratory

Silicosis (simple chronic, accelerated, acute, PMF), silicotuberculosis, COPD, autoimmune disease (silicosis-scleroderma)

OSHA PEL 50 ug/m3 TWA respirable crystalline silica (29 CFR 1910.1053 general industry; 1926.1153 construction — 2016 standard) NIOSH REL 50 ug/m3 TWA (same as OSHA)

ICD-10-CM J62.8 · J65 · J68.1 · M34.83

Key exposures: Stone fabrication (engineered stone / quartz countertops — EPIDEMIC of accelerated silicosis 2018-2026 in CA, FL, TX, NY); Sandblasting (abrasive blasting — banned for many uses); Construction (concrete/masonry cutting, drilling); Mining and quarrying; Foundry work; Hydraulic fracturing (frac sand operations)

Biological markers: Chest X-ray with ILO classification by NIOSH B-reader (small rounded opacities upper zones); HRCT in symptomatic cases; PFT (restrictive +/- obstructive)

NIOSH: NIOSH WoRLD silicosis surveillance; California Silicosis Surveillance Program (post-engineered stone epidemic)

Notification: OSHA 300 M(2); state silicosis registry (MI, NJ, CA reportable); state WC; NIOSH HHE if outbreak

State workers'-comp overlays (1)
  • US-CA — Wet methods mandatory; HEPA vacuum mandatory; medical surveillance enhanced; mandatory reporting to CDPH Cal/OSHA Emergency Standard for Engineered Stone (8 CCR 5204 enhanced) — September 2023 with permanent rulemaking · applies when: CA engineered stone fabrication
4A02

Asbestos (all fiber types)

4A PNEUMOCONIOSES
M(2) Respiratory

Asbestosis, pleural plaques, diffuse pleural thickening, benign asbestos pleural effusion. Mesothelioma + lung cancer in Group 6.

OSHA PEL 0.1 fiber/cc TWA + 1 f/cc 30-min excursion (29 CFR 1910.1001 + 1915.1001 + 1926.1101) NIOSH REL 0.1 f/cc TWA

ICD-10-CM J61 · J92.0 · J94.8

Key exposures: Insulation work (legacy); Shipbuilding (especially WWII era); Construction trades — demolition/renovation of pre-1980 buildings; Asbestos abatement; Auto brake repair (legacy); 9/11 WTC responders/survivors

Biological markers: Chest X-ray ILO classification (B-reader): irregular opacities lower zones; pleural plaques; HRCT; PFT (restrictive); Fiber burden analysis (lung biopsy — historical)

NIOSH: NIOSH WoRLD asbestosis tracking; CDC ATSDR asbestos community surveillance

Notification: OSHA 300; state WC; EPA AHERA (asbestos in schools); EPA TSCA final rule 89 FR 21970 (March 28, 2024; effective May 28, 2024) chrysotile ban; WTC Health Program if 9/11 eligible

4A03

Coal mine dust

4A PNEUMOCONIOSES
M(2) Respiratory

Coal worker's pneumoconiosis (CWP simple and complicated/PMF), 'Black Lung'; dust-related diffuse fibrosis; COPD

MSHA MSHA 30 CFR Parts 70, 71, 72, 75, 90 — dust standard 1.5 mg/m3 (lowered from 2.0 in 2014 final rule)

ICD-10-CM J60 · J64

Key exposures: Underground coal mining; Surface coal mining (less risk); Coal handling

Biological markers: Chest X-ray ILO classification by NIOSH B-reader (small rounded opacities upper zones — different from silica which has more nodular); Spirometry

NIOSH: NIOSH Coal Workers' Health Surveillance Program (CWHSP) — free X-ray and spirometry; resurgence of CWP in central Appalachia documented 2010s-2020s

Notification: MSHA reporting; OWCP Black Lung Benefits Act claim (federal); state WC

State workers'-comp overlays (3)
  • US-PA — PA hosts largest US Black Lung claimant cohort (anthracite NE + bituminous SW); state-level Black Lung benefits supplement federal OWCP; OWCP regional offices intensive; silica co-exposure common in PA mines PA anthracite + bituminous coalfields; PA WC Black Lung Section · applies when: PA coal mining history active or retired
  • US-WV — WV has dedicated Occupational Pneumoconiosis Board for state WC claims; central Appalachia CWP resurgence epicenter (rapid progressive PMF in younger miners 2010s-2020s, silica-driven) WV coalfields + WV Occupational Pneumoconiosis Board · applies when: WV coal miner
  • US-KY — Eastern KY central Appalachia CWP resurgence; KY Pneumoconiosis program; note RECA 2025 (Pub L 119-21) added KY Manhattan Project Waste communities separately KY coalfields + RECA 2025 expansion overlap (MPW communities) · applies when: KY coal miner
4A04

Hard metal (tungsten carbide + cobalt)

4A PNEUMOCONIOSES
M(2) Respiratory

Hard metal lung disease (giant cell interstitial pneumonia, GIP); occupational asthma to cobalt

OSHA PEL Cobalt 0.1 mg/m3 TWA; Tungsten general dust NIOSH REL Cobalt 0.05 mg/m3 TWA (carcinogen consideration)

ICD-10-CM J84.114 · J45.998

Key exposures: Tungsten carbide tool manufacture (saw blades, drill bits); Diamond polishing with cobalt-tungsten binders; Grinding of hard metal tools

Biological markers: BAL with multinucleated giant cells (cannonball cells); HRCT with peripheral GGO and reticulation

Notification: OSHA 300; state WC

4B01

Occupational asthma — HMW sensitizers (proteins, animal-derived, latex, flour)

4B OCCUPATIONAL ASTHMA
M(2) Respiratory

Sensitizer-induced occupational asthma; work-related allergic rhinoconjunctivitis

OSHA std No federal occupational asthma standard — substance-specific where applicable

ICD-10-CM J45.998 · J30.81

Key exposures: Bakers (wheat flour — Baker's asthma); Lab animal workers (rat, mouse urinary proteins); Healthcare (latex prior to powder-free transition); Veterinarians; Pharmaceutical (psyllium); Detergent enzyme manufacture

Biological markers: Spirometry (pre/post shift, serial peak flow 4x/day with work diary); Methacholine challenge; Specific IgE; Specific inhalation challenge (specialized centers)

NIOSH: NIOSH WoRLD Occupational Asthma Surveillance

Notification: OSHA 300; state surveillance (CA SENSOR-Asthma, MI, MA, NJ); state WC

State workers'-comp overlays (1)
  • US-CA — Mandatory reporting by physicians of work-related asthma cases CA SENSOR-Asthma surveillance program (CDPH) · applies when: CA work-related asthma diagnosis
4B02

Occupational asthma — LMW sensitizers (isocyanates, anhydrides, persulfates, metals, drugs)

4B OCCUPATIONAL ASTHMA
M(2) Respiratory

Sensitizer-induced occupational asthma — LMW; reactive airways dysfunction syndrome (RADS) from high-level exposure

ICD-10-CM J45.998 · J68.3

Key exposures: Spray polyurethane foam (isocyanates); Hairdressing (persulfate bleaches); Auto refinish painting; Solder fume (colophony/rosin); Pharmaceutical manufacture

Biological markers: Specific inhalation challenge (gold standard but rare in US); Serial peak flow + spirometry; Specific IgE inconsistently available for LMW

Notification: OSHA 300; state SENSOR-Asthma; state WC

4B03

Work-exacerbated asthma (pre-existing asthma worsened by workplace)

4B OCCUPATIONAL ASTHMA
M(2) Respiratory

Work-exacerbated asthma (WEA) — pre-existing asthma exacerbated by irritants or allergens at work

ICD-10-CM J45.901

Key exposures: Cleaning products (chlorine bleach, ammonia, QUATS); Construction dust; Diesel exhaust; Cold air

Biological markers: Improvement away from work documented; peak flow correlation

Notification: OSHA 300; state SENSOR-Asthma; state WC

4C01

Hypersensitivity pneumonitis (HP) — multiple antigens

4C HYPERSENSITIVITY PNEUMONITIS
M(2) Respiratory

HP: acute (fevers, dyspnea, restrictive), chronic (fibrotic, indistinguishable from IPF if advanced)

ICD-10-CM J67.0 · J67.1 · J67.8 · J67.9

Key exposures: Farmers (moldy hay — Farmer's lung); Bird breeders/owners (Bird fancier's lung); Hot tub maintenance (Hot tub lung — atypical mycobacteria); Maple bark stripping; Metal-working fluid mist (machinist's lung); Mushroom workers; Dental ultrasonic cleaning (legionella)

Biological markers: Serum precipitins to suspected antigen; BAL lymphocytosis; HRCT (ground glass, head cheese, centrilobular nodules)

NIOSH: NIOSH WoRLD HP; NIOSH HHE for cluster investigation

Notification: OSHA 300; state WC; NIOSH HHE

4D01

Diacetyl and 2,3-pentanedione (popcorn lung)

4D OTHER INHALATION
M(2) Respiratory

Bronchiolitis obliterans ('popcorn lung'); obstructive lung disease

OSHA PEL None federal — NIOSH RELs proposed NIOSH REL 5 ppb TWA diacetyl; 9.3 ppb TWA 2,3-pentanedione; 25 ppb STEL diacetyl

ICD-10-CM J44.0 · J84.89

Key exposures: Microwave popcorn manufacture (flavoring application); Flavoring manufacture; Coffee roasting and grinding (diacetyl natural); E-cigarette / vape juice production (legacy concern)

Biological markers: Serial spirometry (fixed obstruction); HRCT mosaic attenuation

NIOSH: NIOSH Criteria Document 2016

Notification: OSHA 300; state WC; NIOSH HHE

4D02

Welding fume (mixed)

4D OTHER INHALATION
M(2) Respiratory

Metal fume fever (acute zinc oxide), siderosis, COPD, increased pneumonia susceptibility (welder's pneumonia)

OSHA PEL Substance-specific (Mn, Cr, Ni) NIOSH REL Substance-specific

ICD-10-CM T59.91XA · J92.9 · J44.9

Key exposures: All welding processes — particularly stainless (Cr/Ni/Mn fume), galvanized (Zn), aluminum, magnesium

Biological markers: Substance-specific where applicable; Chest X-ray (siderosis benign opacities)

Notification: OSHA 300; state WC

4D03

World Trade Center (9/11) dust exposure

4D OTHER INHALATION
M(2) or M(5)

WTC cough, RADS, sinusitis, GERD, ILD, chronic rhinosinusitis, post-traumatic stress co-morbidity

ICD-10-CM J45.998 · K21.9 · J84.9 · J32.9 · F43.10

Key exposures: First responders Sept 11 2001; Recovery and cleanup workers; Lower Manhattan residents and workers (survivors)

Biological markers: WTC Health Program annual exam (CT chest, PFT, mental health screen)

Notification: WTC Health Program enrollment (Zadroga Act); does NOT require state WC

Group 5 — Occupational skin diseases not classified elsewhere 5 entries
5A01

Allergic contact dermatitis — Type IV hypersensitivity

5A CONTACT DERMATITIS
M(1) Skin disorder

Allergic contact dermatitis (ACD)

ICD-10-CM L23.0-L23.9

Key exposures: Healthcare (gloves — accelerators not latex post-2010); Hairdressing (PPD, persulfates, fragrances); Construction (chromate in cement, epoxy resins); Metal work (nickel, cobalt); Cleaning (preservatives, fragrance)

Biological markers: Patch testing T.R.U.E. test or extended series (gold standard for diagnosis)

NIOSH: BLS SOII skin disorders; state SENSOR-Dermatitis (CA, MA, NJ, NY)

Notification: OSHA 300 M(1); state WC

5A02

Irritant contact dermatitis

5A CONTACT DERMATITIS
M(1) Skin disorder

Irritant contact dermatitis (ICD)

ICD-10-CM L24.0-L24.9

Key exposures: Wet work (healthcare, food service, hairdressing); Solvents; Detergents and disinfectants; Cement (alkaline); Acids and alkalis

Biological markers: Negative patch testing; clinical correlation; symptom-exposure-improvement diary

Notification: OSHA 300 M(1); state WC

5B01

Chloracne / MADISH (Metabolizing Acquired Dioxin Induced Skin Hamartomas)

5B OTHER SKIN
M(1)

Chloracne from PCB/PCDD/PCDF exposure

ICD-10-CM L70.8

Key exposures: PCB/dioxin manufacture (legacy); Industrial accidents (Seveso, Yusho, Yu-cheng); Herbicide manufacture (TCDD trace contamination — Agent Orange historical); Transformer servicing pre-1979

Biological markers: Adipose tissue PCB/dioxin (research only)

Notification: OSHA 300; state WC; VA Agent Orange registry if veteran

5B02

Cement burns (chemical burns)

5B OTHER SKIN
M(1)

Alkali chemical burns from prolonged skin contact with wet cement

ICD-10-CM T26.5XXA · L24.7

Key exposures: Construction concrete workers (especially knee contact, deep burns)

Biological markers: Clinical

Notification: OSHA 300; state WC

5B03

Occupational skin cancer (UV) — non-melanoma

5B OTHER SKIN
M(5) Other (cancer recording is complex; many outdoor cancers not specifically attributed)

Cutaneous BCC and SCC in outdoor workers (face, neck, dorsal hands)

ICD-10-CM C44.x

Key exposures: Construction (especially roofers); Agriculture; Postal carriers; Park rangers / forestry; Maritime

Biological markers: Total skin exam annually for high-exposure outdoor workers (ACOEM consensus)

Notification: Cancer registries (SEER for tracked sites); state WC (rare claim approval); some state presumption laws emerging

Group 6 — Diseases caused by occupational carcinogens (IARC Group 1 + NTP RoC occupational entries) 9 entries
6A01

Mesothelioma (asbestos-related)

6A OCCUPATIONAL CANCERS
M(5) Other illness

Malignant pleural mesothelioma; malignant peritoneal mesothelioma; malignant pericardial / tunica vaginalis mesothelioma

ICD-10-CM C45.0 · C45.1 · C45.2

Key exposures: See asbestos exposure list (4A02); even very low exposures associated with mesothelioma; latency 20-50 years

IARC: Group 1 — asbestos all forms (since 1977/2012 reaffirmation)

Biological markers: Pleural fluid cytology + cell block (calretinin, podoplanin, WT-1, mesothelin); Pleural biopsy with immunohistochemistry

Notification: OSHA 300; state WC; state cancer registries (SEER); 9/11 WTCHP if eligible; OWCP if federal worker

6A02

Lung cancer — occupational (multiple agents)

6A OCCUPATIONAL CANCERS
M(5)

Lung cancer attributable to occupational exposure

ICD-10-CM C34.x

Key exposures: Asbestos (all subtypes; synergistic with smoking ~50x); Crystalline silica (IARC 1 since 1997); Cr(VI) (IARC 1); Nickel refining (IARC 1); Arsenic (IARC 1); Cadmium (IARC 1); Beryllium (IARC 1); Diesel engine exhaust (IARC 1 since 2012); Bis(chloromethyl) ether (BCME); Hardwood dust (sinonasal; lung weaker); Plutonium (IARC 1); Radon (uranium mining; also residential); Tobacco smoke + occupational combined risk

IARC: Multiple Group 1 agents

Biological markers: LDCT lung screening for eligible (USPSTF B 50-80, >=20 pack-years)

Notification: OSHA 300; state WC; state cancer registries; WTCHP if 9/11

6A03

Bladder cancer — aromatic amines

6A OCCUPATIONAL CANCERS
M(5)

Urothelial carcinoma of bladder from occupational aromatic amine exposure

ICD-10-CM C67.x

Key exposures: Benzidine and benzidine-based dyes (largely banned); 2-Naphthylamine (banned 1977 OSHA); 4-Aminobiphenyl (banned); Auramine production; MOCA — 4,4'-methylenebis(2-chloroaniline); Rubber industry (legacy aromatic amine exposure); Dye manufacture; Aluminum production

IARC: Group 1 — multiple aromatic amines

Biological markers: Urine cytology screening in known exposed (limited sensitivity)

Notification: OSHA 300; state WC; SEER

6A04

Hematologic malignancies (benzene, ethylene oxide, formaldehyde, 1,3-butadiene)

6A OCCUPATIONAL CANCERS
M(5)

Acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), non-Hodgkin lymphoma

ICD-10-CM C92.0 · C92.9 · D46.9 · C85.9

Key exposures: Benzene (AML, MDS — IARC 1); Ethylene oxide (NHL, AML, breast cancer — IARC 1); Formaldehyde (myeloid leukemia, NPC — IARC 1); 1,3-Butadiene (CML — IARC 1)

Biological markers: CBC surveillance; t(9;22) and other cytogenetics in established cases

Notification: OSHA 300; state WC; SEER

6A05

Sinonasal cancer (wood dust, leather dust, formaldehyde)

6A OCCUPATIONAL CANCERS
M(5)

Sinonasal adenocarcinoma + SCC

ICD-10-CM C30.0 · C31.x

Key exposures: Hardwood dust (IARC 1) — furniture, cabinetry; Leather dust (boot/shoe making — historical); Nickel (IARC 1); Formaldehyde (NPC — IARC 1)

Biological markers: Nasal endoscopy if symptomatic; CT/MRI if mass

Notification: OSHA 300; state WC; SEER

6A06

Laryngeal cancer (asbestos — IARC 2012 elevation)

6A OCCUPATIONAL CANCERS
M(5)

Laryngeal SCC associated with asbestos exposure

ICD-10-CM C32.x

Key exposures: Asbestos — IARC reclassified larynx as causally associated 2012

Notification: OSHA 300; state WC; WTCHP

6A07

Hepatic angiosarcoma (vinyl chloride monomer)

6A OCCUPATIONAL CANCERS
M(5)

Hepatic angiosarcoma (rare, near-pathognomonic for occupational VCM exposure)

ICD-10-CM C22.3

Key exposures: PVC monomer manufacture (sealed since OSHA 1974 rule 1910.1017)

IARC: Group 1

Biological markers: LFTs, AFP, imaging if exposure history

Notification: OSHA 300; state WC; SEER

6B01

Firefighter occupational cancer (state-presumption family)

6B FIREFIGHTER CANCER PRESUMPTIONS
M(5)

Multiple cancer types causally linked to firefighter exposures (PFAS, combustion byproducts, asbestos in legacy fires, diesel exhaust)

ICD-10-CM C-series various

Key exposures: Structural firefighters; Wildland firefighters; Aircraft rescue firefighters

IARC: Group 1 — Occupation of firefighting (IARC 2022 upgrade from 2A to 1)

Presumption cancers: Bladder cancer, Mesothelioma, Testicular cancer, Kidney cancer, Lung cancer (non-smokers), Multiple myeloma, Non-Hodgkin lymphoma, Leukemia, Brain cancer, Prostate cancer (newer additions), Breast cancer (women firefighters), Colorectal cancer

Notification: State WC presumption claim; state firefighter cancer registry (where exists); WTCHP if 9/11

State workers'-comp overlays (15)
  • US-CA — CA Labor Code §3212.1 establishes firefighter cancer presumption using the IARC framework rather than an enumerated cancer list — covers any cancer that develops in active firefighters and former firefighters within the statutory window after employment if a known carcinogen the firefighter was exposed to is reasonably linked to the cancer. AB 1101 (2019) and subsequent amendments expanded covered employers; requires generally 5+ years of service. Note: prior version of this overlay stated '~14 cancers' enumerated — corrected: CA uses framework approach not list CA Labor Code §3212.1 + AB 1101 (2020 additions) + SB 1180 · applies when: CA firefighter active or retired within statute window
  • US-NY — Cancer presumption for FDNY and other career firefighters; covers ~14 cancers NY GML §207-kk (2019 expansion); RPL §3-b · applies when: NY firefighter career
  • US-TX — Cancer presumption for FF including testicular, prostate, NHL, leukemia, MM, lung, brain, bladder, kidney, breast TX GVC §607.055 (Texas WC presumption) · applies when: TX firefighter career 5+ years
  • US-FL — 21 cancers presumption for FL FF >=5 yrs service; mandates lump-sum payment or LTC benefits FL §112.1816 (Firefighter Cancer presumption) · applies when: FL career firefighter
  • US-IL — Cancer presumption applies for IL FF; benefits via firefighter pension code IL Public Safety Employee Benefits Act 820 ILCS 320; Firefighter occupational disease act · applies when: IL firefighter pension-eligible
  • US-NJ — Cancer presumption for firefighters with >=5 years service; covers ~20 enumerated cancers (NY-FL framework family) NJ Thomas P. Canzanella Twenty First Century First Responders Protection Act (P.L.2019, c.182) · applies when: NJ career firefighter active or retired within statutory window
  • US-MA — Cancer presumption for firefighters >=5 yrs service; ~16 enumerated cancers per amendments MA G.L. c. 32 §94 + cancer presumption (1990 + amendments) · applies when: MA career firefighter
  • US-WA — Cancer presumption for firefighters; HB 1913 expanded to ~14+ enumerated cancers WA RCW 51.32.185 + HB 1913 (2021) · applies when: WA career firefighter
  • US-OR — Cancer presumption for firefighters >=5 yrs; SB 870 expanded eligibility OR ORS 656.802 + SB 870 (2021) · applies when: OR career firefighter
  • US-CO — Cancer presumption for firefighters; heart-lung presumption broader CO Revised Statutes §8-41-209 (cancer + heart-lung presumption) · applies when: CO career firefighter
  • US-MN — Cancer presumption for firefighters; HF8 (2024) expanded coverage Minn. Stat. §299A.465 + §176.011 + HF8 (2024) · applies when: MN career firefighter
  • US-AZ — Cancer presumption for firefighters AZ ARS §23-901.06 + §38-1102 · applies when: AZ career firefighter
  • US-VA — Cancer presumption for firefighters; HB 1389 (2020) expanded covered cancers VA Code §65.2-402 + §65.2-402.1 + HB 1389 (2020) · applies when: VA career firefighter
  • US-MI — Cancer presumption + heart-lung presumption for firefighters MCL 418.405 + 418.401(2)(d) · applies when: MI career firefighter
  • US-PA — Cancer presumption for firefighters PA Act 46 of 2011 + Act 184 of 2014 · applies when: PA career firefighter
6C01

Ionizing radiation-induced cancers (multiple sites)

6C RADIATION CANCERS
M(5)

Radiation-induced leukemia, thyroid, breast, lung, GI cancers

ICD-10-CM C-series

Key exposures: Atomic Veterans / DOE nuclear weapons workers (EEOICPA covered); Uranium miners (Radiation Exposure Compensation Act RECA — reauthorized + expanded Pub L 119-21 §§100201-205 (July 4, 2025); ID/UT/NM downwinders + post-1971 uranium workers + new MPW program MO/KY/TN/AK; filing deadline Dec 31, 2027); Medical/nuclear medicine workers (LSS data); 9/11 cleanup ash exposures

Federal compensation: EEOICPA (Energy Employees Occupational Illness Compensation Program Act) — DOE/AWE site workers, lump-sum + medical; RECA (Radiation Exposure Compensation Act) — atomic veterans, uranium miners, downwinders; VA Agent Orange / Atomic Veterans presumption

Notification: OWCP EEOICPA / RECA; OSHA 300; state WC; VA if veteran

Group 7 — Work-related musculoskeletal disorders (WMSDs) — US-SPECIFIC EXTENSION (not in RD 1299/2006) 5 entries
7A01

Carpal tunnel syndrome (CTS) — work-related

7A UPPER LIMB WMSD
M(5) Other (musculoskeletal disorders are M(5) since 2014 rule)

Median nerve compression at the wrist with paresthesia, weakness, nocturnal symptoms

OSHA std No federal ergonomic standard since 2001 Ergonomics Rule revocation; OSHA Ergonomic Guidelines (voluntary)

ICD-10-CM G56.00 · G56.01 · G56.02

Key exposures: Repetitive forceful hand exertion (assembly, meat/poultry processing); Sustained pinch grip; Vibrating tools; Awkward wrist posture (data entry — less consistent evidence)

Biological markers: Nerve conduction study (gold standard); Phalen, Tinel, Durkan compression tests

NIOSH: BLS SOII MSD; California SENSOR-CTS surveillance

Notification: OSHA 300 M(5); state WC

State workers'-comp overlays (1)
  • US-CA — Employer must address RMI / WMSD when 2+ predictable WMSDs occur in workers performing identical work in 12 months Cal/OSHA Ergonomic Standard 8 CCR 5110 (only state standard) · applies when: CA workplace meeting threshold
7A02

Rotator cuff syndrome / impingement

7A UPPER LIMB WMSD
M(5)

Rotator cuff tendinopathy, partial- and full-thickness tears

ICD-10-CM M75.1x · M75.4x

Key exposures: Overhead work (construction, electricians, painters); Repetitive shoulder work (manufacturing assembly); Heavy lifting

Biological markers: Physical exam (Neer, Hawkins, painful arc); MRI if surgical consideration

Notification: OSHA 300 M(5); state WC

7A03

Lateral and medial epicondylitis

7A UPPER LIMB WMSD
M(5)

Lateral epicondylitis ('tennis elbow'), medial epicondylitis ('golfer's elbow')

ICD-10-CM M77.1x · M77.0x

Key exposures: Repetitive forceful gripping with extended wrist; Plumbers, carpenters, butchers, electricians

Biological markers: Cozen's test; Mill's test; pain on resisted wrist extension

Notification: OSHA 300; state WC

7B01

Work-related low back disorders

7B BACK / SPINE WMSD
M(5)

Low back pain with mechanical or radicular features; herniated lumbar disc with radiculopathy

OSHA std No federal ergonomic standard; NIOSH Lifting Equation (RWL) is voluntary risk assessment

ICD-10-CM M54.5x · M51.16 · M51.17

Key exposures: Manual material handling (warehouse, healthcare patient handling); Whole body vibration (truck drivers, heavy equipment); Prolonged static postures (sitting and standing)

Biological markers: MRI lumbar if red flags or surgical consideration; EMG if radiculopathy

NIOSH: BLS SOII back injuries leading category of WMSD lost-time

Notification: OSHA 300 M(5); state WC

7B02

Healthcare patient handling injuries

7B BACK / SPINE WMSD
M(5)

Work-related low back and shoulder injuries in healthcare from patient handling

ICD-10-CM M54.5x · M75.1x

Key exposures: Nurses, nursing aides, physical therapists, EMS

NIOSH: NIOSH safe patient handling: lifting >35 lbs of patient weight requires mechanical assist

Notification: OSHA 300; state WC

State overlays: 11+ states have safe patient handling laws (CA, IL, NY, etc.)

State workers'-comp overlays (3)
  • US-CA — Mandatory safe patient handling policy in all CA acute care hospitals; mandatory lift equipment CA AB 1136 (2011) Safe Patient Handling in Hospitals · applies when: CA hospital
  • US-NY — Mandatory safe patient handling program in healthcare facilities NY Public Health Law §2997-h Safe Patient Handling 2014 · applies when: NY healthcare facility
  • US-IL — Mandatory program with employee involvement IL Hospital Safe Patient Handling Act 210 ILCS 85/6.25 · applies when: IL hospital
Group 8 — Work-related mental health conditions and PTSD — US-SPECIFIC EXTENSION (high state-presumption activity) 3 entries
8A01

First responder PTSD — work-related

8A PTSD / TRAUMATIC STRESS
M(5)

Post-traumatic stress disorder from occupational critical incidents

ICD-10-CM F43.10 · F43.11 · F43.12

Key exposures: Firefighters; EMS personnel; Police officers; Corrections officers; Dispatchers (911 telecommunicators); Emergency department staff; Combat veterans (VA jurisdiction)

Biological markers: PCL-5 (PTSD Checklist DSM-5); CAPS-5 if clinician-administered

Notification: State WC; many states have presumption laws (see overlays); EAP referral standard

State workers'-comp overlays (14)
  • US-CA — Rebuttable PTSD presumption for FF and peace officers; extended sunset 2025-2029 CA SB 542 (2019) Labor Code §3212.15 — PTSD presumption for FF/peace officers · applies when: CA FF or peace officer during covered period
  • US-FL — Workers' comp covers mental injury in first responders even without physical injury (departure from physical-injury-first rule) FL §112.1815 (2018) — first responder mental injury · applies when: FL first responder
  • US-NY — Specific WC procedural rules; no broad presumption but case law favorable NY WC Board PTSD claims for first responders · applies when: NY first responder
  • US-IL — PTSD claims considered; treatment funding via state grants IL First Responder Suicide Prevention Act + WC · applies when: IL first responder
  • US-NJ — Rebuttable presumption of work-related PTSD for first responders exposed to qualifying critical incidents NJ A1116 (2019) — first responder PTSD presumption · applies when: NJ first responder with PTSD post-qualifying event
  • US-MA — PTSD presumption for first responders following qualifying critical incident; WC indemnity + medical MA Chapter 41 §111F + 2018 amendments · applies when: MA first responder
  • US-WA — PTSD presumption for firefighters, law enforcement officers, and EMS personnel WA RCW 51.32.185(1)(b) (2018+) · applies when: WA first responder
  • US-OR — PTSD claims for first responders; presumption framework developing post-2019 OR ORS 656.802 + mental disorder provisions · applies when: OR first responder
  • US-CO — PTSD presumption for first responders post-qualifying event; treatment funding CO HB17-1229 (2017) + amendments · applies when: CO first responder
  • US-MN — PTSD presumption for first responders and corrections officers Minn. Stat. §176.011, subd. 15 (2018+) · applies when: MN first responder or corrections officer
  • US-AZ — PTSD coverage for first responders; presumption + treatment access AZ ARS §23-901.09 (first responder mental health) · applies when: AZ first responder
  • US-VA — PTSD presumption for first responders following qualifying event VA Code §65.2-107 (2020+) · applies when: VA first responder
  • US-MI — PTSD claims considered for first responders; case-specific WC determination MI first responder PTSD WC provisions · applies when: MI first responder
  • US-PA — PTSD/PTSI presumption for first responders and corrections officers PA Act 41 of 2022 — PTSI/PTSD presumption · applies when: PA first responder or corrections officer
8B01

Acute injury or psychological trauma from workplace violence

8B OCCUPATIONAL VIOLENCE
M(5) or as injury per case

Physical injury or acute stress reaction from workplace violence (Type I criminal, Type II customer/client, Type III worker-on-worker, Type IV personal relationship)

OSHA std No federal workplace violence standard; OSHA Workplace Violence in Healthcare and Social Service guidance + active rulemaking

ICD-10-CM Y07.x · T74.x · F43.0 · F43.10

Key exposures: Healthcare (Type II most common — ED, psych, long-term care); Retail/convenience store (Type I robbery); Social services (Type II); Education (multiple types); Public-facing roles

Biological markers: Acute stress disorder screening if traumatic event

Notification: OSHA 300; OSHA 1904.39 if hospitalization/fatality; state WC; law enforcement if criminal

State workers'-comp overlays (3)
  • US-CA — Mandatory written workplace violence prevention plan for healthcare + general industry as of July 2024 Cal/OSHA 8 CCR 3342 Workplace Violence Prevention in Healthcare (2017); SB 553 General Industry WVPP 2024 · applies when: CA covered employer
  • US-NY — Public employers must conduct WV risk evaluation + written program NYS Public Employer Workplace Violence Prevention Act (2009) · applies when: NY public employer
  • US-IL — Healthcare facilities must implement WV prevention program IL Health Care Worker Violence Prevention Act 2018 · applies when: IL healthcare facility
8C01

Occupational burnout — healthcare and high-stress sectors

8C BURNOUT / SECOND VICTIM
M(5) — disputed whether burnout is recordable

Burnout syndrome (emotional exhaustion, depersonalization, low personal accomplishment); secondary traumatic stress; second victim phenomenon

ICD-10-CM Z73.0 · F43.8

Key exposures: Healthcare (HCP burnout heightened post-COVID); EMS and first responders; Teachers (rising 2020-2026); Mental health professionals; Social workers

Biological markers: Copenhagen Burnout Inventory (CBI) — preferred public domain; Maslach Burnout Inventory (MBI) — Mind Garden copyright (avoid for SEED)

Notification: Rarely OSHA 300 (recordability disputed); state WC (rare approval); EAP / wellness program; ACGME wellness for residents

Federal occupational-disease programs

Carve-outs that run outside the state workers'-comp system, with their own eligibility and benefits.

WTCHP

World Trade Center Health Program — federally-funded monitoring and treatment for 9/11 responders and survivors under the James Zadroga 9/11 Health and Compensation Act.

James Zadroga 9/11 Health and Compensation Act →

EEOICPA

Energy Employees Occupational Illness Compensation Program Act — lump-sum + medical benefits for DOE nuclear-weapons / energy workers (paired with the DOE Former Worker screening program).

EEOICPA + DOE FWP →

Black Lung Benefits Act

Coal-miner pneumoconiosis benefits administered by the OWCP (Office of Workers' Compensation Programs), separate from state systems.

30 USC §901 et seq. →

50-state workers'-comp presumption laws

Workers' comp presumption laws shift the burden of proof: instead of the worker proving work causation, the disease is PRESUMED work-related for covered occupations unless the employer/insurer rebuts. Most common categories: firefighter cancer (~48 states with some form), first responder PTSD (~30 states), heart-lung (FF and LEO, ~40 states), COVID-19 essential worker (most states had emergency presumptions 2020-2022, many sunsetted or restricted).

State variation is the rule, not the exception. Firefighter cancer, first-responder PTSD and heart-lung presumptions differ in scope and covered conditions across states (e.g. CA, NY, TX). Flag: state variation — see the specific state workers' compensation commission.

Coding cross-reference — how diseases are catalogued

Dimension🇺🇸 US🇬🇧 UK🇪🇸 ES
Closed legal listNone (synthesis)IIDB PD A1–D12RD 1299/2006
Coding schemeICD-10-CM + Y96/Z57.xPD lettered codesRD grupos 1–6
RecordingOSHA 300 columns M(1)–M(5)RIDDOR report to HSECEPROSS / parte EP
Compensation50-state WC + federal carve-outsIIDB (centralized DWP)Seguridad Social (centralized)

US uses ICD-10-CM diagnostic codes plus Y96 (work environment) and Z57.x (occupational exposure) external-cause codes — there are no US-specific lettered disease codes as in the UK PD scheme or numbered groups as in ES RD 1299/2006.

Under the physician's clinical judgement

  • OH provides advisory capability assessment + accommodation recommendations; the employer makes employment decisions (ACOEM Code of Ethical Conduct).
  • The written opinion shares functional limitations only — never diagnoses (AMA Code of Medical Ethics Opinion 1.2.6 + HIPAA + ADA + GINA segregation).
  • ADA medical-inquiry rules: no medical inquiry pre-offer; post-offer any inquiry if applied uniformly; current employees only if job-related and consistent with business necessity (29 CFR 1630.14).
  • No patient data stored beyond statutory retention (OSHA medical records: employment + 30 years, 29 CFR 1910.1020).

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